Repair after acute lung injury: molecular mechanisms and therapeutic opportunities
Department of Functional Biology, Physiology Area, Faculty of Medicine, University of Oviedo, Julian Claveria s/n, 33006 Oviedo, Spain
Critical Care 2012, 16:209 doi:10.1186/cc11224Published: 20 March 2012
First paragraph (this article has no abstract)
Acute lung injury (ALI) is a clinical syndrome characterized by impairment in gas exchange and/or lung mechanics that leads to hypoxemia and increased work of breathing (WOB). When respiratory failure occurs, most patients require mechanical ventilation. This clinical scenario is related to high morbidity and mortality rates.