Table 5

Summary of animal trials that used different methods to induce intra-arrest hypothermia during cardiac arrest.

Outcome

IATH (%)

IATH (%)


Riter [10]

PFC-TLV

iv fluids


Survival (1-hr, %)

100

100

ROSC (%)

88

25

CoPP (mmHg)

14

8 *


Yannopoulos [13]

Intravascular catheter

iv fluids


ROSC (%)

100

55 *

CoPP (mmHg)

21

15 *

LVEF (%)

32

17 *


Yu [42]

TNEC

iv fluids


Survival (%, 4 days)

57

29

ROSC (%)

100

29 *

CoPP (mmHg)

23

12 *


CoPP, coronary perfusion pressure; LVEF, left ventricular ejection fraction; PFC-TLV, perfluorocarbon-based total liquid ventilation; ROSC, return of spontaneous circulation; TNEC, trans-nasal evaporative cooling; *, P < 0.05

Scolletta et al. Critical Care 2012 16:R41   doi:10.1186/cc11235

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