Table 2 |
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|
Univariate analysis of baseline characteristics and interventions in ALI cases and matched controls |
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|
ALI cases n = 112 |
Controls n = 112 |
Odds ratio |
P value |
|
|
|
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|
Baseline characteristics |
||||
|
Age (years) Median (IQR) |
64.5 (53.5-72.0) |
62.0 (53.0-71.5) |
1.00 (0.98-1.03) |
0.65 |
|
Male gender n (%) |
56 (50) |
61 (55) |
1.43 (0.68-3.3) |
0.52 |
|
BMI Median (IQR) |
26.7 (24.07-31.05) |
26.4 (21.9-30.4) |
1.00 (0.99-1.01) |
0.48 |
|
Ever smoker n (%) |
66 (59) |
52 (46) |
1.24 (0.96-1.65) |
0.07 |
|
Alcohol abuse n (%) |
13 (12) |
9 (8) |
1.28 (0.74-1.93) |
0.37 |
|
Pneumonia type |
0.007a |
|||
|
n (%) |
||||
|
CAP |
33 (29.5) |
55 (49) |
0.32 (0.15-0.63) |
|
|
HCAP |
33 (29.5) |
29 (26) |
1.22 (0.66-2.27) |
|
|
HAP |
46 (41) |
28 (25) |
2.10 (1.19-3.86) |
|
|
Charlson score Median (IQR) |
3 (2-4) |
2 (1-4) |
1.0 (0.88-1.14) |
0.26 |
|
Aspiration n (%) |
8 (7.1) |
4 (3.6) |
1.84 (0.63-6.55) |
0.25 |
|
Diabetes n (%) |
25 (22) |
33 (29) |
0.71 (0.39-1.26) |
0.24 |
|
Immunosuppression n (%) |
52 (46.4) |
50 (44.6) |
1.13 (0.54-2.36) |
0.73 |
|
Pneumonia severity index score Median (IQR) |
115 (92-142) |
101 (76-119) |
1.02 (1.01-1.03) |
< 0.001 a |
|
Shock n (%) |
47 (42) |
9 (8) |
16.3 (5.47-79.04) |
< 0.001 a |
|
Respiratory rate Median (IQR) |
23 (20-28) |
20 (18-24) |
1.04 (1.00-1.08) |
0.05 |
|
SaO2/FiO2 Median (IQR) |
236 (107-336) |
336 (247-448) |
0.995 (0.993-0.997 |
< 0.001 a |
|
Bilateral infiltrates n (%) |
61 (54.5) |
31 (38.2) |
3.67 (1.92-7.61) |
< 0.001 a |
|
Pleural effusion n (%) |
23 (20.5) |
17 (15.4) |
1.34 (0.68-2.69) |
0.38 |
|
Interventions |
||||
|
Time to antibiotics (hours) Median (IQR) |
0 (0-9) |
0 (0-3) |
1.00 (0.99-1.02) |
0.11 |
|
Appropriate initial antimicrobial treatment n (%) |
62 (55.4) |
85 (75.9) |
0.29 (0.13-0.58) |
< 0.001 a |
|
Any transfusion n (%) |
38 (33.9) |
15 (13.4) |
4.53 (2.08-11.59) |
< 0.001 a |
|
Platelets |
15 (13.4) |
4 (3.6) |
6.50 (1.47-59.33) |
0.0098 a |
|
Red blood cells |
31 (27.7) |
13 (11.6) |
4.0 (1.59-11.96) |
0.002 a |
|
Fresh frozen plasma |
10 (8.9) |
1 (0.9) |
- |
0.008 a |
|
Corticosteroids systemic n (%) |
48 (42.9) |
51 (45.5) |
0.89 (0.51-1.55) |
0.67 |
|
Mechanical ventilation n (%) |
95 (85) |
24 (21) |
29.4 (10.2-141.17) |
< 0.001 a |
|
Invasive |
80 (71) |
19 (17) |
18.36 (7.24-66.69) |
|
|
Noninvasive |
15 (14) |
5 (4) |
2.83 (1.13-8.25) |
|
|
|
||||
|
BMI, Body mass index; CAP, community-acquired pneumonia; HAP, hospital-acquired pneumonia; HCAP, healthcare-associated pneumonia; IQR, interquartile range.a a- statistically significant |
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|
Kojicic et al. Critical Care 2012 16:R46 doi:10.1186/cc11247 |
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