Highly Accessed Letter

Fluid resuscitation in septic shock: too much, too little or just right?

John R Prowle

Author Affiliations

Adult Critical Care Unit, The Royal London Hospital, Barts Health, Whitechapel Road, London E1 1BB, UK

Critical Care 2012, 16:436 doi:10.1186/cc11362


See related research by Smith and Perner, http://ccforum.com/content/16/3/R76

Published: 29 June 2012

First paragraph (this article has no abstract)

In their interesting observational study Smith and Perner [1] describe fluid resuscitation (FR) in 164 patients with septic shock, concluding that survival was better in patients receiving higher volumes over the first 72 h. I think we should be cautious, however, to conclude from this that more is better.