Critical Care | Volume 16 Issue 4

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	Volume 16 Issue 4
	Comment
	Editorial The Barcelona Declaration from the World Alliance against Antibiotic Resistance: engagement of intensivists Jean M Carlet, Antonio Artigas, Michael S Niederman, Antoni Torres, on behalf of World Alliance against Antibiotic Resistance Critical Care 2012, 16:145 (3 August 2012) Abstract \| Full text \| PDF \| PubMed
	Viewpoint Vitamin D in sepsis: from basic science to clinical impact Jordan A Kempker, Vin Tangpricha, Thomas R Ziegler, Greg S Martin Critical Care 2012, 16:316 (19 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Viewpoint Permissive hypofiltration Lakhmir S Chawla, John A Kellum, Claudio Ronco Critical Care 2012, 16:317 (26 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	Viewpoint Acetazolamide: a second wind for a respiratory stimulant in the intensive care unit? Nicholas Heming, Saïk Urien, Christophe Faisy Critical Care 2012, 16:318 (7 August 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Early and simple detection of diastolic dysfunction during weaning from mechanical ventilation Gorazd Voga Critical Care 2012, 16:137 (6 July 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary From bench to bedside Colin L Verdant Critical Care 2012, 16:136 (6 July 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary The Swiss bus accident on 13 March 2012: lessons for pre-hospital care Richard M Lyon, Jon Sanders Critical Care 2012, 16:138 (11 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Do earplugs stop noise from driving critical care patients into delirium? Gary H Mills, Richard S Bourne Critical Care 2012, 16:139 (17 July 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary A rapidly progressing lymphocyte exhaustion after severe sepsis Guillaume Monneret, Fabienne Venet Critical Care 2012, 16:140 (23 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Free haemoglobin in 'old' transfused blood - baddy or bystander? Simon J Finney Critical Care 2012, 16:141 (31 July 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Colonization pressure: a critical parameter in the epidemiology of antibiotic-resistant bacteria Marc JM Bonten Critical Care 2012, 16:142 (31 July 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary PSP/reg: a new stone in sepsis biomarkers? Stefano Busani, Massimo Girardis Critical Care 2012, 16:143 (1 August 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Acute kidney injury and residual renal function Claudio Ronco, Mitchell H Rosner Critical Care 2012, 16:144 (3 August 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary How much fluid resuscitation is optimal in septic shock? James A Russell Critical Care 2012, 16:146 (8 August 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Hemofiltration or hemodialysis for acute kidney injury? Achim Jörres Critical Care 2012, 16:147 (10 August 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary AKI patients have worse long-term outcomes, especially in the immediate post-ICU period Eric AJ Hoste, Wouter De Corte Critical Care 2012, 16:148 (27 August 2012) Abstract \| Full text \| PDF \| PubMed
	Review
	Review Pro/con debate: Is etomidate safe in hemodynamically unstable critically ill patients? Gordon Flynn, Yahya Shehabi Critical Care 2012, 16:227 (19 July 2012) Abstract \| Full text \| PDF \| PubMed
	Review Clinical review: Traumatic brain injury in patients receiving antiplatelet medication Christopher Beynon, Daniel N Hertle, Andreas W Unterberg, Oliver W Sakowitz Critical Care 2012, 16:228 (26 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Bench-to-bedside review: Erythropoietin and its derivatives as therapies in critical care Nimesh SA Patel, Kiran K Nandra, Christoph Thiemermann Critical Care 2012, 16:229 (26 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Clinical review: Volume of fluid resuscitation and the incidence of acute kidney injury - a systematic review John R Prowle, Horng-Ruey Chua, Sean M Bagshaw, Rinaldo Bellomo Critical Care 2012, 16:230 (7 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology
	Review Clinical review: Serious adverse events associated with the use of rituximab - a critical care perspective Pashtoon M Kasi, Hussein A Tawbi, Chester V Oddis, Hrishikesh S Kulkarni Critical Care 2012, 16:231 (31 August 2012) Abstract \| Full text \| PDF \| PubMed
	Report
	Correction Correction: Outcome of haematology patients admitted to intensive care in a tertiary centre: primary heamtological diagnosis, recent chemotherapy and bone marrow transplantation are not associated with outcome Ricardo Jose, Isla MacDonald, Paul Pfeffer, Steve Shaw, Banwari Agarwal Critical Care 2012, 16:435 (19 July 2012) Abstract \| Full text \| PDF \| PubMed
	Correction Correction: Patterns of infection and impact on outcome in haematology patients admitted to intensive care Ricardo Jose, Isla MacDonald, Paul Pfeffer, Steve Shaw, Christopher Kibbler, Banwari Agarwal Critical Care 2012, 16:434 (19 July 2012) Abstract \| Full text \| PDF \| PubMed
	Book report A Review of Transfusion Therapy: Clinical Principles and Practice, 3rd edition Alexander L Eastman, Paul E Pepe Critical Care 2012, 16:315 (5 July 2012) Abstract \| Full text \| PDF
	Research
	Research Pancreatic stone protein as an early biomarker predicting mortality in a prospective cohort of patients with sepsis requiring ICU management Yok-Ai Que, Frederik Delodder, Idris Guessous, Rolf Graf, Martha Bain, Thierry Calandra, Lucas Liaudet, Philippe Eggimann Critical Care 2012, 16:R114 (2 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Measurement of pancreatic stone protein/regenerating protein (PSP/reg) within 24 hours of intensive care unit admission may predict risk of death more accurately than procalcitonin and pro-inflammatory cytokines.
	Research The confusion assessment method for the intensive care unit (CAM-ICU) and intensive care delirium screening checklist (ICDSC) for the diagnosis of delirium: a systematic review and meta-analysis of clinical studies Dimitri Gusmao-Flores, Jorge Ibrain Figueira Salluh, Ricardo Chalhub, Lucas C Quarantini Critical Care 2012, 16:R115 (3 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary The confusion assessment method for the intensive care unit is an excellent diagnostic tool for delirium in critically ill ICU patients, suggests a systematic review and meta-analysis.
	Research Benefit of a single recruitment maneuver after an apnea test for the diagnosis of brain death Marie Paries, Nicolas Boccheciampe, Mathieu Raux, Bruno Riou, Olivier Langeron, Armelle Nicolas-Robin Critical Care 2012, 16:R116 (3 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Survival and neurologic outcome after traumatic out-of-hospital cardiopulmonary arrest in a pediatric and adult population: a systematic review Jörn Zwingmann, Alexander T Mehlhorn, Thorsten Hammer, Jörg Bayer, Norbert P Südkamp, Peter C Strohm Critical Care 2012, 16:R117 (6 July 2012) Abstract \| Full text \| PDF \| PubMed \| F1000 Biology
	Research Interest of a simple on-line screening registry for measuring ICU burden related to an influenza pandemic Jean-Christophe Richard, Tài Pham, Christian Brun-Buisson, Jean Reignier, Alain Mercat, Gaëtan Beduneau, Bernard Régnier, Bruno Mourvillier, Christophe Guitton, Matthias Castanier, Alain Combes, Yves Tulzo, Laurent Brochard, the REVA study group Critical Care 2012, 16:R118 (9 July 2012) Abstract \| Full text \| PDF \| PubMed
	Research Prognostic impact of fecal pH in critically ill patients Akinori Osuka, Kentaro Shimizu, Hiroshi Ogura, Osamu Tasaki, Toshimitsu Hamasaki, Takashi Asahara, Koji Nomoto, Masami Morotomi, Yasuyuki Kuwagata, Takeshi Shimazu Critical Care 2012, 16:R119 (10 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Hypoxia-inducible factor (HIF1α) gene expression in human shock states Julien Textoris, Nathalie Beaufils, Gabrielle Quintana, Amin Ben Lassoued, Laurent Zieleskiewicz, Sandrine Wiramus, Valéry Blasco, Nathalie Lesavre, Claude Martin, Jean Gabert, Marc Leone Critical Care 2012, 16:R120 (10 July 2012) Abstract \| Full text \| PDF \| PubMed
	Research Steroidogenesis in the adrenal dysfunction of critical illness: impact of etomidate Nienke Molenaar, Ronald M Bijkerk, Albertus Beishuizen, Christel M Hempen, Margriet FC de Jong, Istvan Vermes, Gertjan van der Sluijs Veer, Armand RJ Girbes, AB Johan Groeneveld Critical Care 2012, 16:R121 (10 July 2012) Abstract \| Full text \| PDF \| PubMed
	Research The impact of statin use on pneumonia risk and outcome: a combined population-based case-control and cohort study Anders Nielsen, Rikke Nielsen, Anders Riis, Søren Johnsen, Henrik Sørensen, Reimar Thomsen Critical Care 2012, 16:R122 (12 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Kidney function decline after a non-dialysis-requiring acute kidney injury is associated with higher long-term mortality in critically ill survivors Chun-Fu Lai, Vin-Cent Wu, Tao-Min Huang, Yu-Chang Yeh, Kuo-Chuan Wang, Yin-Yi Han, Yu-Feng Lin, Ying-Jheng Jhuang, Chia-Ter Chao, Chih-Chung Shiao, Pi-Ru Tsai, Fu-Chang Hu, Nai-Kuan Chou, Wen-Je Ko, Kwan-Dun Wu, the National Taiwan University Hospital Study Group on Acute Renal Failure (NSARF) Critical Care 2012, 16:R123 (12 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research One-year mortality among Danish intensive care patients with acute kidney injury: a cohort study Henrik Gammelager, Christian Christiansen, Martin Johansen, Else Tønnesen, Bente Jespersen, Henrik Sørensen Critical Care 2012, 16:R124 (12 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Free hemoglobin concentration in severe sepsis: methods of measurement and prediction of outcome Michael Adamzik, Tim Hamburger, Frank Petrat, Jürgen Peters, Herbert de Groot, Matthias Hartmann Critical Care 2012, 16:R125 (16 July 2012) Abstract \| Full text \| PDF \| PubMed
	Research Effects of intensivist coverage in a post-anaesthesia care unit on surgical patients' case mix and characteristics of the intensive care unit Marc Kastrup, Matthes Seeling, Stefan Barthel, Andy Bloch, Marie le Claire, Claudia Spies, Matthias Scheller, Jan Braun Critical Care 2012, 16:R126 (18 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research The effect of telemedicine in critically ill patients: systematic review and meta-analysis M Elizabeth Wilcox, Neill KJ Adhikari Critical Care 2012, 16:R127 (18 July 2012) Abstract \| Full text \| PDF \| PubMed
	Research Association of hemoglobin concentration and mortality in critically ill patients with severe traumatic brain injury Mypinder S Sekhon, Nielson McLean, William R Henderson, Dean R Chittock, Donald EG Griesdale Critical Care 2012, 16:R128 (20 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Predicting on-going hemorrhage and transfusion requirement after severe trauma: a validation of six scoring systems and algorithms on the TraumaRegister DGU^® Thomas Brockamp, Ulrike Nienaber, Manuel Mutschler, Arasch Wafaisade, Sigune Peiniger, Rolf Lefering, Bertil Bouillon, Marc Maegele, TraumaRegister DGU Critical Care 2012, 16:R129 (20 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Plasma suPAR levels are associated with mortality, admission time, and Charlson Comorbidity Index in the acutely admitted medical patient: a prospective observational study Thomas Haupt, Janne Petersen, Gertrude Ellekilde, Henrik Klausen, Christian Thorball, Jesper Eugen-Olsen, Ove Andersen Critical Care 2012, 16:R130 (23 July 2012) Abstract \| Full text \| PDF \| PubMed
	Research Identification of haplotype tag single nucleotide polymorphisms within the receptor for advanced glycation end products gene and their clinical relevance in patients with major trauma Ling Zeng, An-qiang Zhang, Wei Gu, Jian Zhou, Lian-yang Zhang, Ding-yuan Du, Mao Zhang, Hai-yan Wang, Jun Yan, Ce Yang, Jian-xin Jiang Critical Care 2012, 16:R131 (24 July 2012) Abstract \| Full text \| PDF \| PubMed
	Research Light and the outcome of the critically ill: an observational cohort study Ricardo A Castro, Derek C Angus, Seo Hong, Chingwen Lee, Lisa A Weissfeld, Gilles Clermont, Matthew R Rosengart Critical Care 2012, 16:R132 (24 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Ventilatory support in critically ill hematology patients with respiratory failure Rosario Molina, Teresa Bernal, Marcio Borges, Rafael Zaragoza, Juan Bonastre, Rosa Granada, Juan Rodriguez-Borregán, Karla Núñez, Iratxe Seijas, Ignacio Ayestaran, Guillermo M Albaiceta, the EMEHU study investigators Critical Care 2012, 16:R133 (24 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Metformin attenuates ventilator-induced lung injury George Tsaknis, Ilias I Siempos, Petros Kopterides, Nikolaos A Maniatis, Christina Magkou, Matina Kardara, Stefania Panoutsou, Anastasia Kotanidou, Charis Roussos, Apostolos Armaganidis Critical Care 2012, 16:R134 (24 July 2012) Abstract \| Full text \| PDF \| PubMed
	Research Measurement of multiple biomarkers in advanced stage heart failure patients treated with pulmonary artery catheter guided therapy Jodi L Zilinski, Ravi V Shah, Hanna K Gaggin, Mary Gantzer, Thomas J Wang, James L Januzzi Critical Care 2012, 16:R135 (25 July 2012) Abstract \| Full text \| PDF \| PubMed \| F1000 Biology
	Research Therapeutic and toxic blood concentrations of nearly 1,000 drugs and other xenobiotics Martin Schulz, Stefanie Iwersen-Bergmann, Hilke Andresen, Achim Schmoldt Critical Care 2012, 16:R136 (26 July 2012) Abstract \| Full text \| PDF \| PubMed
	Research Depletion of neutrophil extracellular traps in vivo results in hypersusceptibility to polymicrobial sepsis in mice Wei Meng, Adnana Paunel-Görgülü, Sascha Flohé, Almuth Hoffmann, Ingo Witte, Colin MacKenzie, Stephan E Baldus, Joachim Windolf, Tim T Lögters Critical Care 2012, 16:R137 (26 July 2012) Abstract \| Full text \| PDF \| PubMed
	Research Role of galactomannan determinations in bronchoalveolar lavage fluid samples from critically ill patients with chronic obstructive pulmonary disease for the diagnosis of invasive pulmonary aspergillosis: a prospective study Hangyong He, Lin Ding, Bing Sun, Fang Li, Qingyuan Zhan Critical Care 2012, 16:R138 (27 July 2012) Abstract \| Full text \| PDF \| PubMed
	Research Effects of endotoxin on lactate metabolism in humans Burkhard Michaeli, Alexandre Martinez, Jean-Pierre Revelly, Marie-Christine Cayeux, René L Chioléro, Luc Tappy, Mette M Berger Critical Care 2012, 16:R139 (27 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology
	Research Sustained low efficiency dialysis using a single-pass batch system in acute kidney injury - a randomized interventional trial: the REnal Replacement Therapy Study in Intensive Care Unit PatiEnts Vedat Schwenger, Markus A Weigand, Oskar Hoffmann, Ralf Dikow, Lars P Kihm, Jörg Seckinger, Nexhat Miftari, Matthias Schaier, Stefan Hofer, Caroline Haar, Peter P Nawroth, Martin Zeier, Eike Martin, Christian Morath Critical Care 2012, 16:R140 (27 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology
	Research Prediction of severe community-acquired pneumonia: a systematic review and meta-analysis Christophe Marti, Nicolas Garin, Olivier Grosgurin, Antoine Poncet, Christophe Combescure, Sebastian Carballo, Arnaud Perrier Critical Care 2012, 16:R141 (27 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Risk factors for onset of hypothermia in trauma victims: The HypoTraum study Frédéric Lapostolle, Jean Sebbah, James Couvreur, François Koch, Dominique Savary, Karim Tazarourte, Gerald Egman, Lynda Mzabi, Michel Galinski, Frédéric Adnet Critical Care 2012, 16:R142 (31 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Neuroventilatory efficiency and extubation readiness in critically ill patients Ling Liu, Huogen Liu, Yi Yang, Yingzi Huang, Songqiao Liu, Jennifer Beck, Arthur S Slutsky, Christer Sinderby, Haibo Qiu Critical Care 2012, 16:R143 (31 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Improved neurologically intact survival with the use of an automated, load-distributing band chest compression device for cardiac arrest presenting to the emergency department Marcus Hock Ong, Stephanie Fook-Chong, Annitha Annathurai, Shiang Ang, Ling Tiah, Kok Yong, Zhi Koh, Susan Yap, Papia Sultana Critical Care 2012, 16:R144 (3 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Mechanical cardiopulmonary resuscitation using a load-distributing band is associated with improved neurologically intact survival in adults; adoption of this device in emergency departments can improve outcomes in cardiac arrest.
	Research Benefits and risks of manual hyperinflation in intubated and mechanically ventilated intensive care unit patients: a systematic review Frederique Paulus, Jan M Binnekade, Margreeth B Vroom, Marcus J Schultz Critical Care 2012, 16:R145 (3 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Hemofiltration compared to hemodialysis for acute kidney injury: systematic review and meta-analysis Jan O Friedrich, Ron Wald, Sean M Bagshaw, Karen EA Burns, Neill KJ Adhikari Critical Care 2012, 16:R146 (6 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology
	Research Elevated cardiac troponin in the early post-operative period and mortality following ruptured abdominal aortic aneurysm: a retrospective population-based cohort study Ilana Kopolovic, Kimberley Simmonds, Shelley Duggan, Mark Ewanchuk, Daniel E Stollery, Sean M Bagshaw Critical Care 2012, 16:R147 (7 August 2012) Abstract \| Full text \| PDF \| PubMed
	Research Endotoxemia and mortality prediction in ICU and other settings: underlying risk and co-detection of gram negative bacteremia are confounders James C Hurley, Bertrand Guidet, Georges Offenstadt, Eric Maury Critical Care 2012, 16:R148 (7 August 2012) Abstract \| Full text \| PDF \| PubMed
	Research Risk assessment in sepsis: a new prognostication rule by APACHE II score and serum soluble urokinase plasminogen activator receptor Evangelos J Giamarellos-Bourboulis, Anna Norrby-Teglund, Vassiliki Mylona, Athina Savva, Iraklis Tsangaris, Ioanna Dimopoulou, Maria Mouktaroudi, Maria Raftogiannis, Marianna Georgitsi, Anna Linnér, George Adamis, Anastasia Antonopoulou, Efterpi Apostolidou, Michael Chrisofos, Chrisostomos Katsenos, Ioannis Koutelidakis, Katerina Kotzampassi, George Koratzanis, Marina Koupetori, Ioannis Kritselis, Korina Lymberopoulou, Konstantinos Mandragos, Androniki Marioli, Jonas Sundén-Cullberg, Anna Mega, Athanassios Prekates, Christina Routsi, Charalambos Gogos, Carl-Johan Treutiger, Apostolos Armaganidis, George Dimopoulos et al. Critical Care 2012, 16:R149 (8 August 2012) Abstract \| Full text \| PDF \| PubMed
	Research Risk factors and outcomes for prolonged versus brief fever: a prospective cohort study Philippe Seguin, Antoine Roquilly, Olivier Mimoz, Pascale Maguet, Karim Asehnoune, Sébastien Biederman, Elsa Carise, Yannick Malledant, the AtlanRea Group Critical Care 2012, 16:R150 (13 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Prognostic utility and characterization of cell-free DNA in patients with severe sepsis Dhruva J Dwivedi, Lisa J Toltl, Laura L Swystun, Janice Pogue, Kao-Lee Liaw, Jeffrey I Weitz, Deborah J Cook, Alison E Fox-Robichaud, Patricia C Liaw, the Canadian Critical Care Translational Biology Group Critical Care 2012, 16:R151 (13 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Interleukin-6 is the strongest predictor of 30-day mortality in patients with cardiogenic shock due to myocardial infarction René P Andrié, Ulrich M Becher, Ricarda Frommold, Vedat Tiyerili, Jan W Schrickel, Georg Nickenig, Jörg O Schwab Critical Care 2012, 16:R152 (13 August 2012) Abstract \| Full text \| PDF \| PubMed
	Research Mild metabolic acidosis impairs the β-adrenergic response in isolated human failing myocardium Hanna Schotola, Karl Toischer, Aron F Popov, André Renner, Jan D Schmitto, Jan Gummert, Michael Quintel, Martin Bauer, Lars S Maier, Samuel Sossalla Critical Care 2012, 16:R153 (13 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Vasopressin and terlipressin in adult vasodilatory shock: a systematic review and meta-analysis of nine randomized controlled trials Ary Serpa Neto, Antônio P Nassar, Sérgio O Cardoso, José A Manetta, Victor GM Pereira, Daniel C Espósito, Maria CT Damasceno, James A Russell Critical Care 2012, 16:R154 (14 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Epidemiology and outcome of severe pneumococcal pneumonia admitted to intensive care unit: a multicenter study Nicolas Mongardon, Adeline Max, Adrien Bouglé, Frédéric Pène, Virginie Lemiale, Julien Charpentier, Alain Cariou, Jean-Daniel Chiche, Jean-Pierre Bedos, Jean-Paul Mira Critical Care 2012, 16:R155 (15 August 2012) Abstract \| Full text \| PDF \| PubMed
	Research A perioperative infusion of sodium bicarbonate does not improve renal function in cardiac surgery patients: a prospective observational cohort study Matthias Heringlake, Hermann Heinze, Maria Schubert, Yvonne Nowak, Janina Guder, Maria Kleinebrahm, Hauke Paarmann, Thorsten Hanke, Julika Schön Critical Care 2012, 16:R156 (16 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research A distinct influenza infection signature in the blood transcriptome of patients with severe community-acquired pneumonia Grant P Parnell, Anthony S McLean, David R Booth, Nicola J Armstrong, Marek Nalos, Stephen J Huang, Jan Manak, Wilson Tang, Oi-Yan Tam, Stanley Chan, Benjamin M Tang Critical Care 2012, 16:R157 (16 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Diacerhein attenuates the inflammatory response and improves survival in a model of severe sepsis Kelly L Calisto, Angélica C Camacho, Francine C Mittestainer, Bruno M Carvalho, Dioze Guadagnini, José B Carvalheira, Mario J Saad Critical Care 2012, 16:R158 (16 August 2012) Abstract \| Full text \| PDF \| PubMed
	Research Mannitol increases renal blood flow and maintains filtration fraction and oxygenation in postoperative acute kidney injury: a prospective interventional study Gudrun Bragadottir, Bengt Redfors, Sven-Erik Ricksten Critical Care 2012, 16:R159 (17 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Alkaline phosphatase activity after cardiothoracic surgery in infants and correlation with post-operative support and inflammation: a prospective cohort study Jesse Davidson, Suhong Tong, Amanda Hauck, D Lawson, James Jaggers, Jon Kaufman, Eduardo da Cruz Critical Care 2012, 16:R160 (20 August 2012) Abstract \| Full text \| PDF \| PubMed
	Research Impact of surveillance of hospital-acquired infections on the incidence of ventilator-associated pneumonia in intensive care units: a quasi-experimental study Thomas Bénet, Bernard Allaouchiche, Laurent Argaud, Philippe Vanhems Critical Care 2012, 16:R161 (21 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Continuous venovenous hemodialysis with regional citrate anticoagulation in patients with liver failure: a prospective observational study Caroline Schultheiß, Bernd Saugel, Veit Phillip, Philipp Thies, Sebastian Noe, Ulrich Mayr, Bernhard Haller, Henrik Einwächter, Roland M Schmid, Wolfgang Huber Critical Care 2012, 16:R162 (22 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Acute management and outcome of multiple trauma patients with pelvic disruptions Markus Burkhardt, Ulrike Nienaber, Antonius Pizanis, Marc Maegele, Ulf Culemann, Bertil Bouillon, Sascha Flohé, Tim Pohlemann, Thomas Paffrath, the TraumaRegister DGU and the German Pelvic Injury Register of the Deutsche Gesellschaft für Unfallchirurgie Critical Care 2012, 16:R163 (22 August 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Low volume resuscitation does not yet seem to be accepted practice in the management of multiple trauma patients with pelvic disruption, despite initial massive fluid resuscitation being associated with worse outcomes.
	Correspondence
	Letter One more idea on preventable ICU deaths ... Jack JM Ligtenberg, Bas W Bens, Jan C Ter Maaten Critical Care 2012, 16:438 (6 July 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Reducing sensory input in critically ill patients: are eyemasks a blind spot? Koen S Simons, Mark van den Boogaard, Cornelis PC de Jager Critical Care 2012, 16:439 (16 July 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Impact of nystatin on Candida and the oral microbiome Christopher D Hingston, Emma J Hingston, Matt P Wise Critical Care 2012, 16:440 (23 July 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Comparison of endotracheal intubation using direct and video laryngoscopes in the ICU Fu-Shan Xue, Yi Cheng, Rui-Ping Li Critical Care 2012, 16:441 (27 July 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Is non-invasive ventilation the best ventilatory support for 'do not intubate' patients? Guillaume Lacroix, Julien Legodec, Erwan D'Aranda, Pierre Esnault, Pierre-Emmanuel Romanat, Philippe Goutorbe Critical Care 2012, 16:442 (8 August 2012) Abstract \| Full text \| PDF \| PubMed
	Letter What is the optimal fluid status in critically ill patients? Yu-Hsiang Chou Critical Care 2012, 16:443 (14 August 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Continuous infusion of meropenem in critically ill patients: practical considerations Fabio Taccone Critical Care 2012, 16:444 (27 August 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Recruitment maneuver after apnea test or continuous positive airway pressure apnea test? Guillaume Lacroix, Erwan d'Aranda, Jean Cotte, Pierre Esnault, Pierre-Emmanuel Romanat, Philippe Goutorbe Critical Care 2012, 16:445 (31 August 2012) Abstract \| Full text \| PDF \| PubMed

	Volume 16 Issue 4
	Comment
	Editorial The Barcelona Declaration from the World Alliance against Antibiotic Resistance: engagement of intensivists Jean M Carlet, Antonio Artigas, Michael S Niederman, Antoni Torres, on behalf of World Alliance against Antibiotic Resistance Critical Care 2012, 16:145 (3 August 2012) Abstract \| Full text \| PDF \| PubMed
	Viewpoint Vitamin D in sepsis: from basic science to clinical impact Jordan A Kempker, Vin Tangpricha, Thomas R Ziegler, Greg S Martin Critical Care 2012, 16:316 (19 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Viewpoint Permissive hypofiltration Lakhmir S Chawla, John A Kellum, Claudio Ronco Critical Care 2012, 16:317 (26 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	Viewpoint Acetazolamide: a second wind for a respiratory stimulant in the intensive care unit? Nicholas Heming, Saïk Urien, Christophe Faisy Critical Care 2012, 16:318 (7 August 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Early and simple detection of diastolic dysfunction during weaning from mechanical ventilation Gorazd Voga Critical Care 2012, 16:137 (6 July 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary From bench to bedside Colin L Verdant Critical Care 2012, 16:136 (6 July 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary The Swiss bus accident on 13 March 2012: lessons for pre-hospital care Richard M Lyon, Jon Sanders Critical Care 2012, 16:138 (11 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Do earplugs stop noise from driving critical care patients into delirium? Gary H Mills, Richard S Bourne Critical Care 2012, 16:139 (17 July 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary A rapidly progressing lymphocyte exhaustion after severe sepsis Guillaume Monneret, Fabienne Venet Critical Care 2012, 16:140 (23 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Free haemoglobin in 'old' transfused blood - baddy or bystander? Simon J Finney Critical Care 2012, 16:141 (31 July 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Colonization pressure: a critical parameter in the epidemiology of antibiotic-resistant bacteria Marc JM Bonten Critical Care 2012, 16:142 (31 July 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary PSP/reg: a new stone in sepsis biomarkers? Stefano Busani, Massimo Girardis Critical Care 2012, 16:143 (1 August 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Acute kidney injury and residual renal function Claudio Ronco, Mitchell H Rosner Critical Care 2012, 16:144 (3 August 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary How much fluid resuscitation is optimal in septic shock? James A Russell Critical Care 2012, 16:146 (8 August 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary Hemofiltration or hemodialysis for acute kidney injury? Achim Jörres Critical Care 2012, 16:147 (10 August 2012) Abstract \| Full text \| PDF \| PubMed
	Commentary AKI patients have worse long-term outcomes, especially in the immediate post-ICU period Eric AJ Hoste, Wouter De Corte Critical Care 2012, 16:148 (27 August 2012) Abstract \| Full text \| PDF \| PubMed
	Review
	Review Pro/con debate: Is etomidate safe in hemodynamically unstable critically ill patients? Gordon Flynn, Yahya Shehabi Critical Care 2012, 16:227 (19 July 2012) Abstract \| Full text \| PDF \| PubMed
	Review Clinical review: Traumatic brain injury in patients receiving antiplatelet medication Christopher Beynon, Daniel N Hertle, Andreas W Unterberg, Oliver W Sakowitz Critical Care 2012, 16:228 (26 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Bench-to-bedside review: Erythropoietin and its derivatives as therapies in critical care Nimesh SA Patel, Kiran K Nandra, Christoph Thiemermann Critical Care 2012, 16:229 (26 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Clinical review: Volume of fluid resuscitation and the incidence of acute kidney injury - a systematic review John R Prowle, Horng-Ruey Chua, Sean M Bagshaw, Rinaldo Bellomo Critical Care 2012, 16:230 (7 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology
	Review Clinical review: Serious adverse events associated with the use of rituximab - a critical care perspective Pashtoon M Kasi, Hussein A Tawbi, Chester V Oddis, Hrishikesh S Kulkarni Critical Care 2012, 16:231 (31 August 2012) Abstract \| Full text \| PDF \| PubMed
	Report
	Correction Correction: Outcome of haematology patients admitted to intensive care in a tertiary centre: primary heamtological diagnosis, recent chemotherapy and bone marrow transplantation are not associated with outcome Ricardo Jose, Isla MacDonald, Paul Pfeffer, Steve Shaw, Banwari Agarwal Critical Care 2012, 16:435 (19 July 2012) Abstract \| Full text \| PDF \| PubMed
	Correction Correction: Patterns of infection and impact on outcome in haematology patients admitted to intensive care Ricardo Jose, Isla MacDonald, Paul Pfeffer, Steve Shaw, Christopher Kibbler, Banwari Agarwal Critical Care 2012, 16:434 (19 July 2012) Abstract \| Full text \| PDF \| PubMed
	Book report A Review of Transfusion Therapy: Clinical Principles and Practice, 3rd edition Alexander L Eastman, Paul E Pepe Critical Care 2012, 16:315 (5 July 2012) Abstract \| Full text \| PDF
	Research
	Research Pancreatic stone protein as an early biomarker predicting mortality in a prospective cohort of patients with sepsis requiring ICU management Yok-Ai Que, Frederik Delodder, Idris Guessous, Rolf Graf, Martha Bain, Thierry Calandra, Lucas Liaudet, Philippe Eggimann Critical Care 2012, 16:R114 (2 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Measurement of pancreatic stone protein/regenerating protein (PSP/reg) within 24 hours of intensive care unit admission may predict risk of death more accurately than procalcitonin and pro-inflammatory cytokines.
	Research The confusion assessment method for the intensive care unit (CAM-ICU) and intensive care delirium screening checklist (ICDSC) for the diagnosis of delirium: a systematic review and meta-analysis of clinical studies Dimitri Gusmao-Flores, Jorge Ibrain Figueira Salluh, Ricardo Chalhub, Lucas C Quarantini Critical Care 2012, 16:R115 (3 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary The confusion assessment method for the intensive care unit is an excellent diagnostic tool for delirium in critically ill ICU patients, suggests a systematic review and meta-analysis.
	Research Benefit of a single recruitment maneuver after an apnea test for the diagnosis of brain death Marie Paries, Nicolas Boccheciampe, Mathieu Raux, Bruno Riou, Olivier Langeron, Armelle Nicolas-Robin Critical Care 2012, 16:R116 (3 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Survival and neurologic outcome after traumatic out-of-hospital cardiopulmonary arrest in a pediatric and adult population: a systematic review Jörn Zwingmann, Alexander T Mehlhorn, Thorsten Hammer, Jörg Bayer, Norbert P Südkamp, Peter C Strohm Critical Care 2012, 16:R117 (6 July 2012) Abstract \| Full text \| PDF \| PubMed \| F1000 Biology
	Research Interest of a simple on-line screening registry for measuring ICU burden related to an influenza pandemic Jean-Christophe Richard, Tài Pham, Christian Brun-Buisson, Jean Reignier, Alain Mercat, Gaëtan Beduneau, Bernard Régnier, Bruno Mourvillier, Christophe Guitton, Matthias Castanier, Alain Combes, Yves Tulzo, Laurent Brochard, the REVA study group Critical Care 2012, 16:R118 (9 July 2012) Abstract \| Full text \| PDF \| PubMed
	Research Prognostic impact of fecal pH in critically ill patients Akinori Osuka, Kentaro Shimizu, Hiroshi Ogura, Osamu Tasaki, Toshimitsu Hamasaki, Takashi Asahara, Koji Nomoto, Masami Morotomi, Yasuyuki Kuwagata, Takeshi Shimazu Critical Care 2012, 16:R119 (10 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Hypoxia-inducible factor (HIF1α) gene expression in human shock states Julien Textoris, Nathalie Beaufils, Gabrielle Quintana, Amin Ben Lassoued, Laurent Zieleskiewicz, Sandrine Wiramus, Valéry Blasco, Nathalie Lesavre, Claude Martin, Jean Gabert, Marc Leone Critical Care 2012, 16:R120 (10 July 2012) Abstract \| Full text \| PDF \| PubMed
	Research Steroidogenesis in the adrenal dysfunction of critical illness: impact of etomidate Nienke Molenaar, Ronald M Bijkerk, Albertus Beishuizen, Christel M Hempen, Margriet FC de Jong, Istvan Vermes, Gertjan van der Sluijs Veer, Armand RJ Girbes, AB Johan Groeneveld Critical Care 2012, 16:R121 (10 July 2012) Abstract \| Full text \| PDF \| PubMed
	Research The impact of statin use on pneumonia risk and outcome: a combined population-based case-control and cohort study Anders Nielsen, Rikke Nielsen, Anders Riis, Søren Johnsen, Henrik Sørensen, Reimar Thomsen Critical Care 2012, 16:R122 (12 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Kidney function decline after a non-dialysis-requiring acute kidney injury is associated with higher long-term mortality in critically ill survivors Chun-Fu Lai, Vin-Cent Wu, Tao-Min Huang, Yu-Chang Yeh, Kuo-Chuan Wang, Yin-Yi Han, Yu-Feng Lin, Ying-Jheng Jhuang, Chia-Ter Chao, Chih-Chung Shiao, Pi-Ru Tsai, Fu-Chang Hu, Nai-Kuan Chou, Wen-Je Ko, Kwan-Dun Wu, the National Taiwan University Hospital Study Group on Acute Renal Failure (NSARF) Critical Care 2012, 16:R123 (12 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research One-year mortality among Danish intensive care patients with acute kidney injury: a cohort study Henrik Gammelager, Christian Christiansen, Martin Johansen, Else Tønnesen, Bente Jespersen, Henrik Sørensen Critical Care 2012, 16:R124 (12 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Free hemoglobin concentration in severe sepsis: methods of measurement and prediction of outcome Michael Adamzik, Tim Hamburger, Frank Petrat, Jürgen Peters, Herbert de Groot, Matthias Hartmann Critical Care 2012, 16:R125 (16 July 2012) Abstract \| Full text \| PDF \| PubMed
	Research Effects of intensivist coverage in a post-anaesthesia care unit on surgical patients' case mix and characteristics of the intensive care unit Marc Kastrup, Matthes Seeling, Stefan Barthel, Andy Bloch, Marie le Claire, Claudia Spies, Matthias Scheller, Jan Braun Critical Care 2012, 16:R126 (18 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research The effect of telemedicine in critically ill patients: systematic review and meta-analysis M Elizabeth Wilcox, Neill KJ Adhikari Critical Care 2012, 16:R127 (18 July 2012) Abstract \| Full text \| PDF \| PubMed
	Research Association of hemoglobin concentration and mortality in critically ill patients with severe traumatic brain injury Mypinder S Sekhon, Nielson McLean, William R Henderson, Dean R Chittock, Donald EG Griesdale Critical Care 2012, 16:R128 (20 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Predicting on-going hemorrhage and transfusion requirement after severe trauma: a validation of six scoring systems and algorithms on the TraumaRegister DGU^® Thomas Brockamp, Ulrike Nienaber, Manuel Mutschler, Arasch Wafaisade, Sigune Peiniger, Rolf Lefering, Bertil Bouillon, Marc Maegele, TraumaRegister DGU Critical Care 2012, 16:R129 (20 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Plasma suPAR levels are associated with mortality, admission time, and Charlson Comorbidity Index in the acutely admitted medical patient: a prospective observational study Thomas Haupt, Janne Petersen, Gertrude Ellekilde, Henrik Klausen, Christian Thorball, Jesper Eugen-Olsen, Ove Andersen Critical Care 2012, 16:R130 (23 July 2012) Abstract \| Full text \| PDF \| PubMed
	Research Identification of haplotype tag single nucleotide polymorphisms within the receptor for advanced glycation end products gene and their clinical relevance in patients with major trauma Ling Zeng, An-qiang Zhang, Wei Gu, Jian Zhou, Lian-yang Zhang, Ding-yuan Du, Mao Zhang, Hai-yan Wang, Jun Yan, Ce Yang, Jian-xin Jiang Critical Care 2012, 16:R131 (24 July 2012) Abstract \| Full text \| PDF \| PubMed
	Research Light and the outcome of the critically ill: an observational cohort study Ricardo A Castro, Derek C Angus, Seo Hong, Chingwen Lee, Lisa A Weissfeld, Gilles Clermont, Matthew R Rosengart Critical Care 2012, 16:R132 (24 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Ventilatory support in critically ill hematology patients with respiratory failure Rosario Molina, Teresa Bernal, Marcio Borges, Rafael Zaragoza, Juan Bonastre, Rosa Granada, Juan Rodriguez-Borregán, Karla Núñez, Iratxe Seijas, Ignacio Ayestaran, Guillermo M Albaiceta, the EMEHU study investigators Critical Care 2012, 16:R133 (24 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Metformin attenuates ventilator-induced lung injury George Tsaknis, Ilias I Siempos, Petros Kopterides, Nikolaos A Maniatis, Christina Magkou, Matina Kardara, Stefania Panoutsou, Anastasia Kotanidou, Charis Roussos, Apostolos Armaganidis Critical Care 2012, 16:R134 (24 July 2012) Abstract \| Full text \| PDF \| PubMed
	Research Measurement of multiple biomarkers in advanced stage heart failure patients treated with pulmonary artery catheter guided therapy Jodi L Zilinski, Ravi V Shah, Hanna K Gaggin, Mary Gantzer, Thomas J Wang, James L Januzzi Critical Care 2012, 16:R135 (25 July 2012) Abstract \| Full text \| PDF \| PubMed \| F1000 Biology
	Research Therapeutic and toxic blood concentrations of nearly 1,000 drugs and other xenobiotics Martin Schulz, Stefanie Iwersen-Bergmann, Hilke Andresen, Achim Schmoldt Critical Care 2012, 16:R136 (26 July 2012) Abstract \| Full text \| PDF \| PubMed
	Research Depletion of neutrophil extracellular traps in vivo results in hypersusceptibility to polymicrobial sepsis in mice Wei Meng, Adnana Paunel-Görgülü, Sascha Flohé, Almuth Hoffmann, Ingo Witte, Colin MacKenzie, Stephan E Baldus, Joachim Windolf, Tim T Lögters Critical Care 2012, 16:R137 (26 July 2012) Abstract \| Full text \| PDF \| PubMed
	Research Role of galactomannan determinations in bronchoalveolar lavage fluid samples from critically ill patients with chronic obstructive pulmonary disease for the diagnosis of invasive pulmonary aspergillosis: a prospective study Hangyong He, Lin Ding, Bing Sun, Fang Li, Qingyuan Zhan Critical Care 2012, 16:R138 (27 July 2012) Abstract \| Full text \| PDF \| PubMed
	Research Effects of endotoxin on lactate metabolism in humans Burkhard Michaeli, Alexandre Martinez, Jean-Pierre Revelly, Marie-Christine Cayeux, René L Chioléro, Luc Tappy, Mette M Berger Critical Care 2012, 16:R139 (27 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology
	Research Sustained low efficiency dialysis using a single-pass batch system in acute kidney injury - a randomized interventional trial: the REnal Replacement Therapy Study in Intensive Care Unit PatiEnts Vedat Schwenger, Markus A Weigand, Oskar Hoffmann, Ralf Dikow, Lars P Kihm, Jörg Seckinger, Nexhat Miftari, Matthias Schaier, Stefan Hofer, Caroline Haar, Peter P Nawroth, Martin Zeier, Eike Martin, Christian Morath Critical Care 2012, 16:R140 (27 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology
	Research Prediction of severe community-acquired pneumonia: a systematic review and meta-analysis Christophe Marti, Nicolas Garin, Olivier Grosgurin, Antoine Poncet, Christophe Combescure, Sebastian Carballo, Arnaud Perrier Critical Care 2012, 16:R141 (27 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Risk factors for onset of hypothermia in trauma victims: The HypoTraum study Frédéric Lapostolle, Jean Sebbah, James Couvreur, François Koch, Dominique Savary, Karim Tazarourte, Gerald Egman, Lynda Mzabi, Michel Galinski, Frédéric Adnet Critical Care 2012, 16:R142 (31 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Neuroventilatory efficiency and extubation readiness in critically ill patients Ling Liu, Huogen Liu, Yi Yang, Yingzi Huang, Songqiao Liu, Jennifer Beck, Arthur S Slutsky, Christer Sinderby, Haibo Qiu Critical Care 2012, 16:R143 (31 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Improved neurologically intact survival with the use of an automated, load-distributing band chest compression device for cardiac arrest presenting to the emergency department Marcus Hock Ong, Stephanie Fook-Chong, Annitha Annathurai, Shiang Ang, Ling Tiah, Kok Yong, Zhi Koh, Susan Yap, Papia Sultana Critical Care 2012, 16:R144 (3 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Mechanical cardiopulmonary resuscitation using a load-distributing band is associated with improved neurologically intact survival in adults; adoption of this device in emergency departments can improve outcomes in cardiac arrest.
	Research Benefits and risks of manual hyperinflation in intubated and mechanically ventilated intensive care unit patients: a systematic review Frederique Paulus, Jan M Binnekade, Margreeth B Vroom, Marcus J Schultz Critical Care 2012, 16:R145 (3 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Hemofiltration compared to hemodialysis for acute kidney injury: systematic review and meta-analysis Jan O Friedrich, Ron Wald, Sean M Bagshaw, Karen EA Burns, Neill KJ Adhikari Critical Care 2012, 16:R146 (6 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology
	Research Elevated cardiac troponin in the early post-operative period and mortality following ruptured abdominal aortic aneurysm: a retrospective population-based cohort study Ilana Kopolovic, Kimberley Simmonds, Shelley Duggan, Mark Ewanchuk, Daniel E Stollery, Sean M Bagshaw Critical Care 2012, 16:R147 (7 August 2012) Abstract \| Full text \| PDF \| PubMed
	Research Endotoxemia and mortality prediction in ICU and other settings: underlying risk and co-detection of gram negative bacteremia are confounders James C Hurley, Bertrand Guidet, Georges Offenstadt, Eric Maury Critical Care 2012, 16:R148 (7 August 2012) Abstract \| Full text \| PDF \| PubMed
	Research Risk assessment in sepsis: a new prognostication rule by APACHE II score and serum soluble urokinase plasminogen activator receptor Evangelos J Giamarellos-Bourboulis, Anna Norrby-Teglund, Vassiliki Mylona, Athina Savva, Iraklis Tsangaris, Ioanna Dimopoulou, Maria Mouktaroudi, Maria Raftogiannis, Marianna Georgitsi, Anna Linnér, George Adamis, Anastasia Antonopoulou, Efterpi Apostolidou, Michael Chrisofos, Chrisostomos Katsenos, Ioannis Koutelidakis, Katerina Kotzampassi, George Koratzanis, Marina Koupetori, Ioannis Kritselis, Korina Lymberopoulou, Konstantinos Mandragos, Androniki Marioli, Jonas Sundén-Cullberg, Anna Mega, Athanassios Prekates, Christina Routsi, Charalambos Gogos, Carl-Johan Treutiger, Apostolos Armaganidis, George Dimopoulos et al. Critical Care 2012, 16:R149 (8 August 2012) Abstract \| Full text \| PDF \| PubMed
	Research Risk factors and outcomes for prolonged versus brief fever: a prospective cohort study Philippe Seguin, Antoine Roquilly, Olivier Mimoz, Pascale Maguet, Karim Asehnoune, Sébastien Biederman, Elsa Carise, Yannick Malledant, the AtlanRea Group Critical Care 2012, 16:R150 (13 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Prognostic utility and characterization of cell-free DNA in patients with severe sepsis Dhruva J Dwivedi, Lisa J Toltl, Laura L Swystun, Janice Pogue, Kao-Lee Liaw, Jeffrey I Weitz, Deborah J Cook, Alison E Fox-Robichaud, Patricia C Liaw, the Canadian Critical Care Translational Biology Group Critical Care 2012, 16:R151 (13 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Interleukin-6 is the strongest predictor of 30-day mortality in patients with cardiogenic shock due to myocardial infarction René P Andrié, Ulrich M Becher, Ricarda Frommold, Vedat Tiyerili, Jan W Schrickel, Georg Nickenig, Jörg O Schwab Critical Care 2012, 16:R152 (13 August 2012) Abstract \| Full text \| PDF \| PubMed
	Research Mild metabolic acidosis impairs the β-adrenergic response in isolated human failing myocardium Hanna Schotola, Karl Toischer, Aron F Popov, André Renner, Jan D Schmitto, Jan Gummert, Michael Quintel, Martin Bauer, Lars S Maier, Samuel Sossalla Critical Care 2012, 16:R153 (13 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Vasopressin and terlipressin in adult vasodilatory shock: a systematic review and meta-analysis of nine randomized controlled trials Ary Serpa Neto, Antônio P Nassar, Sérgio O Cardoso, José A Manetta, Victor GM Pereira, Daniel C Espósito, Maria CT Damasceno, James A Russell Critical Care 2012, 16:R154 (14 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Epidemiology and outcome of severe pneumococcal pneumonia admitted to intensive care unit: a multicenter study Nicolas Mongardon, Adeline Max, Adrien Bouglé, Frédéric Pène, Virginie Lemiale, Julien Charpentier, Alain Cariou, Jean-Daniel Chiche, Jean-Pierre Bedos, Jean-Paul Mira Critical Care 2012, 16:R155 (15 August 2012) Abstract \| Full text \| PDF \| PubMed
	Research A perioperative infusion of sodium bicarbonate does not improve renal function in cardiac surgery patients: a prospective observational cohort study Matthias Heringlake, Hermann Heinze, Maria Schubert, Yvonne Nowak, Janina Guder, Maria Kleinebrahm, Hauke Paarmann, Thorsten Hanke, Julika Schön Critical Care 2012, 16:R156 (16 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research A distinct influenza infection signature in the blood transcriptome of patients with severe community-acquired pneumonia Grant P Parnell, Anthony S McLean, David R Booth, Nicola J Armstrong, Marek Nalos, Stephen J Huang, Jan Manak, Wilson Tang, Oi-Yan Tam, Stanley Chan, Benjamin M Tang Critical Care 2012, 16:R157 (16 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Diacerhein attenuates the inflammatory response and improves survival in a model of severe sepsis Kelly L Calisto, Angélica C Camacho, Francine C Mittestainer, Bruno M Carvalho, Dioze Guadagnini, José B Carvalheira, Mario J Saad Critical Care 2012, 16:R158 (16 August 2012) Abstract \| Full text \| PDF \| PubMed
	Research Mannitol increases renal blood flow and maintains filtration fraction and oxygenation in postoperative acute kidney injury: a prospective interventional study Gudrun Bragadottir, Bengt Redfors, Sven-Erik Ricksten Critical Care 2012, 16:R159 (17 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Alkaline phosphatase activity after cardiothoracic surgery in infants and correlation with post-operative support and inflammation: a prospective cohort study Jesse Davidson, Suhong Tong, Amanda Hauck, D Lawson, James Jaggers, Jon Kaufman, Eduardo da Cruz Critical Care 2012, 16:R160 (20 August 2012) Abstract \| Full text \| PDF \| PubMed
	Research Impact of surveillance of hospital-acquired infections on the incidence of ventilator-associated pneumonia in intensive care units: a quasi-experimental study Thomas Bénet, Bernard Allaouchiche, Laurent Argaud, Philippe Vanhems Critical Care 2012, 16:R161 (21 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Continuous venovenous hemodialysis with regional citrate anticoagulation in patients with liver failure: a prospective observational study Caroline Schultheiß, Bernd Saugel, Veit Phillip, Philipp Thies, Sebastian Noe, Ulrich Mayr, Bernhard Haller, Henrik Einwächter, Roland M Schmid, Wolfgang Huber Critical Care 2012, 16:R162 (22 August 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research Acute management and outcome of multiple trauma patients with pelvic disruptions Markus Burkhardt, Ulrike Nienaber, Antonius Pizanis, Marc Maegele, Ulf Culemann, Bertil Bouillon, Sascha Flohé, Tim Pohlemann, Thomas Paffrath, the TraumaRegister DGU and the German Pelvic Injury Register of the Deutsche Gesellschaft für Unfallchirurgie Critical Care 2012, 16:R163 (22 August 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Low volume resuscitation does not yet seem to be accepted practice in the management of multiple trauma patients with pelvic disruption, despite initial massive fluid resuscitation being associated with worse outcomes.
	Correspondence
	Letter One more idea on preventable ICU deaths ... Jack JM Ligtenberg, Bas W Bens, Jan C Ter Maaten Critical Care 2012, 16:438 (6 July 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Reducing sensory input in critically ill patients: are eyemasks a blind spot? Koen S Simons, Mark van den Boogaard, Cornelis PC de Jager Critical Care 2012, 16:439 (16 July 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Impact of nystatin on Candida and the oral microbiome Christopher D Hingston, Emma J Hingston, Matt P Wise Critical Care 2012, 16:440 (23 July 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Comparison of endotracheal intubation using direct and video laryngoscopes in the ICU Fu-Shan Xue, Yi Cheng, Rui-Ping Li Critical Care 2012, 16:441 (27 July 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Is non-invasive ventilation the best ventilatory support for 'do not intubate' patients? Guillaume Lacroix, Julien Legodec, Erwan D'Aranda, Pierre Esnault, Pierre-Emmanuel Romanat, Philippe Goutorbe Critical Care 2012, 16:442 (8 August 2012) Abstract \| Full text \| PDF \| PubMed
	Letter What is the optimal fluid status in critically ill patients? Yu-Hsiang Chou Critical Care 2012, 16:443 (14 August 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Continuous infusion of meropenem in critically ill patients: practical considerations Fabio Taccone Critical Care 2012, 16:444 (27 August 2012) Abstract \| Full text \| PDF \| PubMed
	Letter Recruitment maneuver after apnea test or continuous positive airway pressure apnea test? Guillaume Lacroix, Erwan d'Aranda, Jean Cotte, Pierre Esnault, Pierre-Emmanuel Romanat, Philippe Goutorbe Critical Care 2012, 16:445 (31 August 2012) Abstract \| Full text \| PDF \| PubMed

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