Table 3

Plasma concentrations of biomarkers and severity scores, by survival status

Biomarker or severity scoring system

All (n = 107)

Death (n = 22)

Survival (n = 85)

Median

IQR

Median

IQR

P value

Acute-phase proteins

CRP, mg/L

203

188

266

154

0.21

PCT, ng/mL

17.485

51.75

26.22

44.75

0.57

PSP/reg, ng/mL

397

435.9

216.1

379

0.02

Cytokines

TNF-α, pg/ml

2.655

10.36

2.35

6.73

0.46

IL-1β, pg/mL

0.795

34.02

7.6

20.41

0.46

IL-6, pg/mL

2,415.58

16,219.42

790.53

6,467.74

0.16

IL-8, pg/mL

757.775

10,597.73

414.88

1,597.6

0.11

IL-10, pg/mL

416.18

1393.6

136.76

494.89

0.17

Other

Leukocytes, G/L

13.85

14.45

13.4

14.2

0.27

APACHE II

32

12

27

13

0.4

SAPS II

71.5

26

68

27

0.52

SAPS III

87.5

27

74

25

0.01

SOFA

11

6

11

4

0.9

APACHE II, Acute Physiology and Chronic Health Evaluation II; CRP, C-reactive protein; IL, interleukin; IQR, interquartile range; PCT, procalcitonin; PSP/reg, pancreatic stone protein/regenerating protein; SAPS, Simplified Acute Physiology Score; SOFA, Sequential Organ Failure Assessment; TNF-α, tumor necrosis factor-alpha.

Que et al. Critical Care 2012 16:R114   doi:10.1186/cc11406