Assessment of hemodynamic efficacy and safety of 6% hydroxyethyl starch 130/0.4 vs. 0.9% NaCl fluid replacement in patients with severe sepsis: how to guide fluid therapy?
Department of Anesthesiology and Intensive Care Medicine, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany
Critical Care 2012, 16:464 doi:10.1186/cc11836
See related research by Guidet et al., http://ccforum.com/content/16/3/R94Published: 15 November 2012
First paragraph (this article has no abstract)
We argue that assessing the hemodynamic efficacy of hydroxyethyl starch (HES) versus NaCl in patients with severe sepsis requires an algorithm to direct the timing and amount of fluid resuscitation. Such an algorithm may include hemodynamic flow parameters.