Table 1

Studies applying hypothermia on day of aneurysm rupture to patients with poor-grade SAH (WFNS 4 to 5 or H&H IV to V)

Study

Number of patients (n)

Target temperature (°C)

Duration of hypothermia (days)

Favorable outcome*, % (n)

Mortality rate, % (n)

Nagao and colleagues (2000)

9

32 to 34

5 to 14

44.4% (4)

55.6% (5)

Yasui and colleagues (2002)

7

33 to 34

2

42.8% (3)*

0.0% (0)

Nakamura and colleagues (2002)

3

32 to 34

5 to 14

0.0% (0)

66.7% (2)

Anei and colleagues (2010)

19

34

2

5.3% (1)

57.9% (11)

Total

38

21.1% (8)

47.4% (18)

*GOS ≥4 or mRS ≤3.

Seule and Keller Critical Care 2012 16(Suppl 2):A16   doi:10.1186/cc11274