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Highly Accessed Commentary

Managing blood glucose in critically ill patients with or without diabetes

Simon Finfer12* and Laurent Billot1

Author Affiliations

1 The George Institute for Global Health, University of Sydney, PO Box M201, Missenden Road, Sydney, NSW 2050, Australia

2 Intensive Therapy Unit, Level 6, Acute Services Building, Royal North Shore Hospital, Pacific Highway, St. Leonards, NSW 2065, Australia

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Critical Care 2013, 17:134  doi:10.1186/cc12591


See related research by Krinsley et al., http://ccforum.com/content/17/2/R37

Published: 18 April 2013

Abstract

Relationships between blood glucose concentration and outcome and also the optimum management of blood glucose remain highly contentious issues for critical care practitioners. Among the many controversies is whether critically ill patients with diabetes should be treated differently from those without diabetes. Krinsley and colleagues assembled a large observational database that sheds further light on the relationships of hyperglycemia, hypoglycemia and glucose variability and risk of death in critically ill patients with and without diabetes. Defining the optimum treatment and whether this should differ by diabetic status requires high-quality primary interventional research.