Table 1

Changes of respiratory index in surfactant-depleted lung injury rabbits ventilated with CMV or HFO

Mode of

Before first LL

15 min after LL

4 h after LL

ventilation

CMV

450.5 ± 25.2

91.8 ± 21.1^*

32.3 ± 6.7^†‡

HFO

430.3 ± 15.2

104.0 ± 13.1^*

55.8 ± 4.3^†

After the completion of surfactant depletion, the rabbits were ventilated by conventional mechanical ventilation (CMV) or by high-frequency oscillatory ventilation (HFO) for 4 h at the same mean airway pressure. LL = lung lavage. ^*P < 0.05 vs the value before the first LL; ^†P < 0.05 vs the value before and 15 min after the first LL; ^‡P < 0.05 vs the values of HFO at 4 h after the first LL.

Shimaoku et al. Critical Care 1998 2:35   doi:10.1186/cc122