Table 3

Documented conditions associated with low SVR

Condition
Comment

Sepsis
Most common cause of low SVR
Pancreatitis
Seen with necrotizing or hemorrhagic

pancreatitis
Cirrhosis
Seen with decompensated liver disease
Adrenal insufficiency
Only 15 well documented cases
Head injury
Seen after initial rise in SVR
Beriberi
Rapid response to thiamine
Salicylate (chronic)
Seen in elderly patients, illness mimics sepsis
TMP-SMX
Reported only in AIDS patients
Vasoplegic syndrome
Occurs within 6 h postcardiopulmonary

bypass

Incidence estimated to be 0.4%-5.0%

SVR, systemic vascular resistance (dynes × s/cm5); TMP-SMX, trimethoprim-sulfamethoxazole. See text for discussion.

Melo and Peters Critical Care 1999 3:71   doi:10.1186/cc343

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