Table


Pre-op
End-CPB
1 h post-CPB
2 h post-CPB
24 h post-CPB

NGF (pg/ml)
199.5
1023.3
3198.9
3382.2
1398.6
Cl
(64.7-615.2)
(429.6-2437.2)
(1692.8-6045.0)
(1838.6-6221.6)
(504.5-3827.4)
P value

≤ 0.05
≤ 0.05
≤ 0.05
≤ 0.05
IL-6 (pg/ml)
4.1
40.4
167.5
252.4
66.1
Cl
(1.4-12.2)
(17.0-96.3)
(101.6-276.0)
(152.1-418.8)
(39.9-109.6)
P value

≤ 0.05
≤ 0.05
≤ 0.05
≤ 0.05
IL-8 (pg/ml)
5.5
36.0
111.1
97.2
20.3
Cl
(2.0-15.2)
(20.6-62.7)
(74.9-165.0)
(57.0-165.6)
(8.1-50.9)
P value

≤ 0.05
≤ 0.05
≤ 0.05
≤ 0.05

Data are expressed as geometric means of log-transformed values with 95% confidence interval (CI). Single factor analysis of variance (ANOVA) and Student t test were used, as appropriate, to determine differences in NGF and cytokine levels at different time points. A P value ≤ 0.05 was accepted as significant.

Codispoti et al. Critical Care 1999 3(Suppl A):P12   doi:10.1186/cc323