Figure 1.

Changes in the relationship between partial carbon dioxide tension(pCO2) and H+ concentration as function of changes in'buffer' strength. Individual curves are drawn for varyingconcentration of total nonvolatile buffers in mmol/l. Note that as theconcentration of 'buffer' increases, the slope of the curveincreases, making changes in H+ concentration more responsive tochanges in CO2.

Kellum Critical Care 2000 4:6   doi:10.1186/cc644