Table 1

Coagulation data


T1
T2
T3
p T1 versus T2
p T2 versus T3
p T1 versus T3

Hb (g/l)
125 (14.6)
91.5 (12.8)
112.8 (15.5)
< 0.0001
< 0.0001
< 0.0001
INR
1.1 (1.1-1.2)
1.7 (1.6-1.8)
1.5 (1.4-1.7)
< 0.0001
< 0.0001
< 0.0001
APTTR
1.1 (1.0-1.2)
1.33 (1.23-1.47)
1.26 (1.18-1.34)
0.001
0.010
0.005
Factor VII (U)
99 (21.6)
67 (17)
72 (20)
< 0.0001
0.0046
< 0.0001
Factor IX (U)
124 (107-136)
114 (107-132)
112 (101-127)
0.90
0.21
0.12
Fibrinogen (g/l)
3 (2.8-3.5)
2.1 (1.9-2.6)
2.2 (1.8-2.5)
< 0.0001
0.7
<0.0001
Platelet count (109/l)
178 (48)
110 (40)
128 (39)
< 0.0001
< 0.0001
< 0.0001
TEG MA (mm)
68 (66-70)
63 (60.5-68)
61 (59-63.5)
< 0.0001
0.011
< 0.0001
Antithrombin (U)
87 (83-93)
61 (10.9)
62 (11.7)
< 0.0001
0.57
< 0.0001
Activated protein C (U)
89.6 (17)
53 (12)
57 (13)
< 0.0001
0.009
< 0.0001
Albumin (g/l)
33 (30-33)
22 (21-23)
22.6 (3.7)
< 0.0001
0.548
< 0.0001
Calcium (mmol/l)
1.18 (1.16-1.2)
1.18 (1.15-1.9)
1.14 (0.06)
0.2639
0.0005
0.0007

Results are presented as means (SD) for normally distributed data and median (95%CI) for skewed data. Hb, haemoglobin; INR, international normalized ratio; APTTR, activated partial thromboplastin time ratio; TEG MA, thromboelastogram maximum amplitude.

Bates et al. Critical Care 2001 5(Suppl C):6   doi:10.1186/cc1035