|
Possible signs of sepsis (adapted from [7]) |
|
| Parameters |
Signs |
|
|
|
| General |
Fever, chills |
| Inflammatory |
Altered white blood cell count, increased serum concentrations of C-reactive protein or procalcitonin |
| Coagulopathy |
Increased D-dimers, low protein C, increased prothrombin time/activated partial thromboplastin time |
| Hemodynamic |
Tachycardia, increased cardiac output, low systemic vascular resistance, low oxygen extraction ratio |
| Metabolic |
Increased insulin requirements |
| Tissue perfusion |
Altered skin perfusion, reduced urine output |
| Organ dysfunction |
Increased urea and creatinine, low platelet count or other coagulation abnormalities, hyperbilirubinemia |
Vincent et al. Critical Care 2002 6(Suppl 3):S1 doi:10.1186/cc1860 |
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