Table 3

Therapeutic interventions: standard therapy versus EGDT

Intervention
0–6 hours
7–72 hours
0–72 hours

Fluid therapy (l)
-2.49a
+1.98b
+0.085
Receiving vasopressors (%)
+2.9
+13.8d
+14.5c
Receiving inotropes (%)
-12.9a
-6.1
-6.2
Receiving red blood cell transfusion (%)
-45.6a
-21.7a
-23.9a
Mechanical ventilation instituted (%)
+0.8
+14.6a
+15.0c
Pulmonary artery catheter use (%)
+3.4
+10.6e
+13.9b

A negative or positive value indicates how the control group therapy compares with the treatment group. a P < 0.001, b P = 0.01, c P = 0.02, d P = 0.03, e P = 0.04. EGDT, early goal-directed therapy.

Vincent et al. Critical Care 2002 6(Suppl 3):S1   doi:10.1186/cc1860