|
Outcome measures: percentage change or improvement, baseline to 72 hours |
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| Outcome measure |
Control |
Treatment |
P value |
|
|
|||
| ScvO2 * |
32.7 |
44.9 |
0.001 |
| Lactate* |
43.5 |
61.0 |
0.02 |
| Base deficit* |
42.7 |
77.5 |
0.001 |
| pH* |
5.4 |
12.3 |
0.001 |
| APACHE II* |
24.5 |
40.2 |
0.002 |
| Mortality in hospital |
46.5 |
30.5 |
0.009 |
| Mortality at 28 days |
49.2 |
33.3 |
0.01 |
| Mortality at 60 days |
56.9 |
44.3 |
0.03 |
| Length of hospital stay† |
- |
20.7 |
0.04 |
|
APACHE II, Acute Physiology and Chronic Health Evaluation; ScvO2, central venous oxygen saturation. * Baseline to 72 hours. †Surviving to hospital discharge. | |||
Vincent et al. Critical Care 2002 6(Suppl 3):S1 doi:10.1186/cc1860 |
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