Appendix 2 Table 1 |
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Optimized levels for central venous pressure, mean arterial pressure, and central venous oxygen saturation (ScvO2) |
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Variable |
Protocol |
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Central venous pressure |
8–12 mmHg (achieved by giving a 500 ml bolus of crystalloid every 30 min) |
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Mean arterial pressure |
≥ 65 ≤ 90 mmHg (if < 65 mmHg, give vasopressors; if > 90 mmHg, give vasodilators) |
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ScvO2 |
If < 70%, transfuse with red cells to reach an hematocrit of ≥ 30% |
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Vincent et al. Critical Care 2002 6(Suppl 3):S1 doi:10.1186/cc1860 |
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