Table 2

Characteristics of patients with impairment in renal function after initiation of colistin

Serum creatinine (mg/dl)

Patient

Characteristics

Cr1

Cr2

Cr3

8

Age 52 years, female, trauma, VAP, septic shock

0.9

2.1

1.4

17

Age 61 years, male, trauma, catheter-related sepsis, diabetes mellitus

1.1

2.3

1.5

24

Age 74 years, male, aneurysm of the abdominal aorta, elective operation.

2.4

5.1

CVVHD, death

Sepsis of unknown primary origin, previous myocardial infarction, hypertension

Cr1, serum creatinine at initiation of colistin; Cr2, highest value of creatinine during treatment with colistin; Cr3, serum creatinine 7 days after completion of treatment with colistin; CVVHD, continuous venovenous hemodiafiltration; VAP, ventilator-associated pneumonia.

Markou et al. Critical Care 2003 7:R78   doi:10.1186/cc2358