|
|
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| Placebo (n = 11) |
Hydrocortisone (n = 11) |
P |
|
|
|
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| NF-kκB (1 hour; %) |
66 (27/125) |
75 (50/98) |
NS |
| NF-kκB (24 hours; %) |
86 (61/116) |
59 (34/105) |
NS |
| TNF-α (4 hours) |
45 (31/66) |
31 (28/40) |
NS |
| TNF-α (24 hours) |
41 (17/45) |
27 (16/40) |
NS |
| IL-6 (pg/ml; 4 hours) |
438 (396/931) |
178 (93/375) |
<0.01 |
| IL-6 (pg/ml; 24 hours) |
281(245/454) |
139 (104/231) |
<0.05 |
| IL-10 (pg/ml; 4 hours) |
16 (9/42) |
137 (79/215) |
<0.001 |
| IL-10 (pg/ml; 24 hours) |
3.5 (2/10) |
3.5 (1/12) |
NS |
Weis et al. Critical Care 2003 7(Suppl 1):5 doi:10.1186/cc2151 |
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