|
Haemodynamic parameters during the study period (safety population) |
||
| Remifentanil (n = 115) |
Fentanyl (n = 81) |
|
|
|
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| Mean arterial pressure |
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| Overall weighted mean MAP (mmHg; range) |
80.9 (38–128) |
79.6 (54–104) |
| % of time in which MAP was within 10% of mean baseline value (range) |
43.1 (0–100) |
48.7 (4–91) |
| Number of patients with MAP ≤ 50 mmHg |
19 (17%) |
8 (10%) |
| Number of patients with MAP ≥ 100 mmHg |
81 (70%) |
52 (64%) |
| Heart rate |
||
| Overall weighted mean HR (beats/min; range) |
88.3 (63–117) |
88.6 (59–129) |
| % of time in which HR was within 10% of mean baseline value (range) |
54.4 (0–100) |
55.6 (5–100) |
| Number of patients with HR ≤ 50 beats/min |
2 (2%) |
3 (4%) |
| Number of patients with HR ≥ 120 beats/min |
35 (30%) |
28 (35%) |
|
The statistical significance of the differences between groups for the mean percentages of time with heart rate (HR) and mean arterial pressure (MAP) within 10% of baseline was not tested. There were no statistically significant differences between groups for any of the other parameters. | ||
Muellejans et al. Critical Care 2004 8:R1 doi:10.1186/cc2398 |
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