Table 6

Haemodynamic parameters during the study period (safety population)

Remifentanil (n = 115)

Fentanyl (n = 81)

Mean arterial pressure

Overall weighted mean MAP (mmHg; range)

80.9 (38–128)

79.6 (54–104)

% of time in which MAP was within 10% of mean baseline value (range)

43.1 (0–100)

48.7 (4–91)

Number of patients with MAP ≤ 50 mmHg

19 (17%)

8 (10%)

Number of patients with MAP ≥ 100 mmHg

81 (70%)

52 (64%)

Heart rate

Overall weighted mean HR (beats/min; range)

88.3 (63–117)

88.6 (59–129)

% of time in which HR was within 10% of mean baseline value (range)

54.4 (0–100)

55.6 (5–100)

Number of patients with HR ≤ 50 beats/min

2 (2%)

3 (4%)

Number of patients with HR ≥ 120 beats/min

35 (30%)

28 (35%)

The statistical significance of the differences between groups for the mean percentages of time with heart rate (HR) and mean arterial pressure (MAP) within 10% of baseline was not tested. There were no statistically significant differences between groups for any of the other parameters.

Muellejans et al. Critical Care 2004 8:R1   doi:10.1186/cc2398