Critical Care

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Acute renal failure – definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group

Rinaldo Bellomo*, Claudio Ronco, John A Kellum, Ravindra L Mehta, Paul Palevsky and the ADQI workgroup

Critical Care 2004, 8:R204-R212 doi:10.1186/cc2872

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Acute kidney injury biomarkers: renal angina and the need for a renal troponin I

Stuart L Goldstein BMC Medicine 2011, 9:135 (21 December 2011)

This article is part of a collection on Clinical biomarkers

Novel biomarkers can be used for prognosis of acute kidney injury (AKI), and in our latest addition to the Clinical Biomarkers series, Stuart L Goldstein discusses the importance of such biomarkers in early detection of AKI.

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Vitamin D deficiency is associated with mortality in the medical intensive care unit

Sindhaghatta Venkatram, Sridhar Chilimuri, Muhammad Adrish, Abayomi Salako, Madanmohan Patel, Gilda Diaz-Fuentes Critical Care 2011, 15:R292 (10 December 2011)

Case report   Open Access

Tenofovir induced acute kidney injury in a patient with unilateral renal agenesis despite initially non-impaired renal function

BT Schleenvoigt, A Stallmach, MW Pletz European Journal of Medical Research 2011, 16:564 (2 December 2011)

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Acute kidney injury in septua- and octogenarians after cardiac surgery

Michael Ried, Thomas Puehler, Assad Haneya, Christof Schmid, Claudius Diez BMC Cardiovascular Disorders 2011, 11:52 (11 August 2011)

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Urine hepcidin has additive value in ruling out cardiopulmonary bypass-associated acute kidney injury: an observational cohort study

Anja Haase-Fielitz, Peter R Mertens, Michael Plaß, Hermann Kuppe, Roland Hetzer, Mark Westerman, Vaughn Ostland, John R Prowle, Rinaldo Bellomo, Michael Haase Critical Care 2011, 15:R186 (4 August 2011)

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Early versus late renal replacement therapy in acute kidney injury: the search for a definition of timing continues

Jonathan Bannard-Smith, Stephen Mousdale Critical Care 2011, 15:437 (29 July 2011)

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Diagnostic performance of fractional excretion of urea in the evaluation of critically ill patients with acute kidney injury: a multicenter cohort study

Michael Darmon, Francois Vincent, Jean Dellamonica, Frederique Schortgen, Frederic Gonzalez, Vincent Das, Fabrice Zeni, Laurent Brochard, Gilles Bernardin, Yves Cohen, Benoit Schlemmer Critical Care 2011, 15:R178 (27 July 2011)

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Oliguria as predictive biomarker of acute kidney injury in critically ill patients

John R Prowle, Yan-Lun Liu, Elisa Licari, Sean M Bagshaw, Moritoki Egi, Michael Haase, Anja Haase-Fielitz, John A Kellum, Dinna Cruz, Claudio Ronco, Kenji Tsutsui, Shigehiko Uchino, Rinaldo Bellomo Critical Care 2011, 15:R172 (19 July 2011)

Oliguria is relatively frequent in intensive care unit patients but most episodes are not followed by acute kidney injury (AKI), suggesting that low urine output alone is only a fair predictor of AKI.

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The ratio of CRP to prealbumin levels predict mortality in patients with hospital-acquired acute kidney injury

Qionghong Xie, Ying Zhou, Zhongye Xu, Yanjiao Yang, Dingwei Kuang, Huaizhou You, Shuai Ma, Chuanming Hao, Yong Gu, Shanyan Lin, Feng Ding BMC Nephrology 2011, 12:30 (29 June 2011)

A high ratio of C-reactive protein (CRP) to prealbumin is associated with mortality in patients with acute kidney injury (AKI) independently of illness severity, suggesting this ratio should be added to the sequential organ failure assessment score.

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Clinical review: Timing of renal replacement therapy

Michael Joannidis, Lui G Forni Critical Care 2011, 15:223 (10 June 2011)

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Are we sedating more than just the brain?

Nathan E Brummel, Timothy D Girard Critical Care 2011, 15:163 (7 June 2011)

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Controversies in acute kidney injury: the 2011 Brussels Roundtable

John A Kellum, Claudio Ronco Critical Care 2011, 15:155 (20 April 2011)

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Long-term risk of mortality after acute kidney injury in patients with sepsis: a contemporary analysis

José António Lopes, Paulo Fernandes, Sofia Jorge, Cristina Resina, Carla Santos, Álvaro Pereira, José Neves, Francisco Antunes, António Gomes da Costa BMC Nephrology 2010, 11:9 (2 June 2010)

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To dose or not to dose: that is the (starch) question ...

Lewis J Kaplan Critical Care 2010, 14:148 (6 May 2010)

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Resuscitation with low volume hydroxyethylstarch 130 kDa/0.4 is not associated with acute kidney injury

Nicolas Boussekey, Raphaël Darmon, Joachim Langlois, Serge Alfandari, Patrick Devos, Agnes Meybeck, Arnaud Chiche, Hugues Georges, Olivier Leroy Critical Care 2010, 14:R40 (18 March 2010)

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Serum neutrophil gelatinase-associated lipocalin at inception of renal replacement therapy predicts survival in critically ill patients with acute kidney injury

Philipp Kümpers, Carsten Hafer, Alexander Lukasz, Ralf Lichtinghagen, Korbinian Brand, Danilo Fliser, Robert Faulhaber-Walter, Jan T Kielstein Critical Care 2010, 14:R9 (1 February 2010)

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Protective effect of resin adsorption on septic plasma-induced tubular injury

Vincenzo Cantaluppi, Viktoria Weber, Carola Lauritano, Federico Figliolini, Silvia Beltramo, Luigi Biancone, Massimo De Cal, Dinna Cruz, Claudio Ronco, Giuseppe Segoloni, Ciro Tetta, Giovanni Camussi Critical Care 2010, 14:R4 (11 January 2010)

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RIFLE is not RIFLE: on the comparability of results

Lars Englberger, Rakesh M Suri, Hartzell V Schaff Critical Care 2009, 13:429 (9 December 2009)

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Hemostasis during low molecular weight heparin anticoagulation for continuous venovenous hemofiltration: a randomized cross-over trial comparing two hemofiltration rates

Heleen M Oudemans-van Straaten, Muriel van Schilfgaarde, Pascal J Molenaar, Jos PJ Wester, Anja Leyte Critical Care 2009, 13:R193 (3 December 2009)

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Association of arterial blood pressure and vasopressor load with septic shock mortality: a post hoc analysis of a multicenter trial

Martin W Dünser, Esko Ruokonen, Ville Pettilä, Hanno Ulmer, Christian Torgersen, Christian A Schmittinger, Stephan Jakob, Jukka Takala Critical Care 2009, 13:R181 (16 November 2009)

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Effect of cardiopulmonary bypass on activated partial thromboplastin time waveform analysis, serum procalcitonin and C-reactive protein concentrations

Bertrand Delannoy, Marie-Laurence Guye, Davy Slaiman, Jean-Jacques Lehot, Maxime Cannesson Critical Care 2009, 13:R180 (13 November 2009)

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A proposed algorithm for initiation of renal replacement therapy in adult critically ill patients

Sean M Bagshaw, Dinna N Cruz, RT Noel Gibney, Claudio Ronco Critical Care 2009, 13:317 (11 November 2009)

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Early release of high mobility group box nuclear protein 1 after severe trauma in humans: role of injury severity and tissue hypoperfusion

Mitchell J Cohen, Karim Brohi, Carolyn S Calfee, Pamela Rahn, Brian B Chesebro, Sarah C Christiaans, Michel Carles, Marybeth Howard, Jean-François Pittet Critical Care 2009, 13:R174 (4 November 2009)

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Late initiation of renal replacement therapy is associated with worse outcomes in acute kidney injury after major abdominal surgery

Chih-Chung Shiao, Vin-Cent Wu, Wen-Yi Li, Yu-Feng Lin, Fu-Chang Hu, Guang-Huar Young, Chin-Chi Kuo, Tze-Wah Kao, Down-Ming Huang, Yung-Ming Chen, Pi-Ru Tsai, Shuei-Liong Lin, Nai-Kuan Chou, Tzu-Hsin Lin, Yu-Chang Yeh, Chih-Hsien Wang, Anne Chou, Wen-Je Ko, Kwan-Dun Wu, Critical Care 2009, 13:R171 (30 October 2009)

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Year in review 2008: Critical Care - nephrology

Zaccaria Ricci, Claudio Ronco Critical Care 2009, 13:227 (21 October 2009)

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RIFLE and AKIN - maintain the momentum and the GFR!

John W Pickering, Zoltan H Endre Critical Care 2009, 13:416 (11 September 2009)

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Intensive care adult patients with severe respiratory failure caused by Influenza A (H1N1)v in Spain

Jordi Rello, Alejandro Rodríguez, Pedro Ibañez, Lorenzo Socias, Javier Cebrian, Asunción Marques, José Guerrero, Sergio Ruiz-Santana, Enrique Marquez, Frutos Del Nogal-Saez, Francisco Alvarez-Lerma, Sergio Martínez, Miquel Ferrer, Manuel Avellanas, Rosa Granada, Enrique Maraví-Poma, Patricia Albert, Rafael Sierra, Loreto Vidaur, Patricia Ortiz, Isidro Prieto del Portillo, Beatriz Galván, Cristóbal León-Gil, Critical Care 2009, 13:R148 (11 September 2009)

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Continuous terlipressin versus vasopressin infusion in septic shock (TERLIVAP): a randomized, controlled pilot study

Andrea Morelli, Christian Ertmer, Sebastian Rehberg, Matthias Lange, Alessandra Orecchioni, Valeria Cecchini, Alessandra Bachetoni, Mariadomenica D'Alessandro, Hugo Van Aken, Paolo Pietropaoli, Martin Westphal Critical Care 2009, 13:R130 (10 August 2009)

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Clinical review: RIFLE and AKIN – time for reappraisal

Dinna N Cruz, Zaccaria Ricci, Claudio Ronco Critical Care 2009, 13:211 (25 June 2009)

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Does intensive insulin therapy really reduce the incidence of acute renal injury in critically ill patients? An analysis using the rifle criteria

JRA Azevedo, RP Azevedo, LC Lucena, NNR Costa, WS Sousa Critical Care 2009, 13(Suppl 3):P37 (23 June 2009)

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The impact of early hypoglycemia and blood glucose variability on outcome in critical illness

Sean M Bagshaw, Rinaldo Bellomo, Michael J Jacka, Moritoki Egi, Graeme K Hart, Carol George, Critical Care 2009, 13:R91 (17 June 2009)

Early hypoglycemia and blood glucose variability show a clinically relevant association with increased mortality in critically ill patients, while the severity of hypoglycemia in particular corresponds closely to the extent of this increase.

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Determinants of postoperative acute kidney injury

Fernando Abelha, Miguela Botelho, Vera Fernandes, Henrique Barros Critical Care 2009, 13:R79 (22 May 2009)

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Continuous venovenous hemofiltration in severely burned patients with acute kidney injury: a cohort study

Kevin K Chung, Jonathan B Lundy, James R Matson, Evan M Renz, Christopher E White, Booker T King, David J Barillo, John A Jones, Leopoldo C Cancio, Lorne H Blackbourne, Steven E Wolf Critical Care 2009, 13:R62 (1 May 2009)

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Delivered dose of renal replacement therapy and mortality in critically ill patients with acute kidney injury

Sergio Vesconi, Dinna N Cruz, Roberto Fumagalli, Detlef Kindgen-Milles, Gianpaola Monti, Anibal Marinho, Filippo Mariano, Marco Formica, Mariano Marchesi, René Robert, Sergio Livigni, Claudio Ronco, Critical Care 2009, 13:R57 (15 April 2009)

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Very old patients admitted to intensive care in Australia and New Zealand: a multi-centre cohort analysis

Sean M Bagshaw, Steve AR Webb, Anthony Delaney, Carol George, David Pilcher, Graeme K Hart, Rinaldo Bellomo Critical Care 2009, 13:R45 (1 April 2009)

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RIFLE classification can predict hospital mortality of critically ill patients

HY Xu, JM Peng, ZR Mao, L Weng, XY Hu, B Du Critical Care 2009, 13(Suppl 1):P264 (13 March 2009)

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Tight perioperative glucose control is associated with a reduction in renal impairment and renal failure in non-diabetic cardiac surgical patients

Patrick Lecomte, Bruno Van Vlem, Jose Coddens, Guy Cammu, Guy Nollet, Frank Nobels, Hugo Vanermen, Luc Foubert Critical Care 2008, 12:R154 (4 December 2008)

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Acute kidney injury in burns: a story of volume and inflammation

Kirsten Colpaert, Eric A Hoste Critical Care 2008, 12:192 (25 November 2008)

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Correlation between the AKI classification and outcome

Marlies Ostermann, Rene Chang, Critical Care 2008, 12:R144 (20 November 2008)

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Year in review 2007: Critical Care – nephrology

Zaccaria Ricci, Claudio Ronco Critical Care 2008, 12:230 (14 October 2008)

Research article   Open Access

Case mix, outcome and activity for patients with severe acute kidney injury during the first 24 hours after admission to an adult, general critical care unit: application of predictive models from a secondary analysis of the ICNARC Case Mix Programme Database

Nitin V Kolhe, Paul E Stevens, Alex V Crowe, Graham W Lipkin, David A Harrison Critical Care 2008, 12(Suppl 1):S2 (13 October 2008)

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Acute kidney injury is common, parallels organ dysfunction or failure, and carries appreciable mortality in patients with major burns: a prospective exploratory cohort study

I Steinvall, Z Bak, F Sjoberg Critical Care 2008, 12:R124 (10 October 2008)

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The need to reform our assessment of evidence from clinical trials: A commentary

Sean M Bagshaw, Rinaldo Bellomo Philosophy, Ethics, and Humanities in Medicine 2008, 3:23 (30 September 2008)

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Acute kidney injury in intensive care unit patients: a comparison between the RIFLE and the Acute Kidney Injury Network classifications

José Lopes, Paulo Fernandes, Sofia Jorge, Sara Gonçalves, António Alvarez, Zélia Costa e Silva, Carlos França, Mateus Prata Critical Care 2008, 12:R110 (28 August 2008)

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Early acute kidney injury and sepsis: a multicentre evaluation

Sean M Bagshaw, Carol George, Rinaldo Bellomo, Critical Care 2008, 12:R47 (10 April 2008)

Patients with septic acute kidney injury (AKI) have a higher burden of illness than patients with non-septic AKI, an evaluation of more than 120,000 intensive care unit admissions has found.

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Circulating plasma factors induce tubular and glomerular alterations in septic burns patients

Filippo Mariano, Vincenzo Cantaluppi, Maurizio Stella, Giuseppe Romanazzi, Barbara Assenzio, Monica Cairo, Luigi Biancone, Giorgio Triolo, V Marco Ranieri, Giovanni Camussi Critical Care 2008, 12:R42 (25 March 2008)

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Plasma neutrophil gelatinase-associated lipocalin predicts acute kidney injury, morbidity and mortality after pediatric cardiac surgery: a prospective uncontrolled cohort study

Catherine L Dent, Qing Ma, Sudha Dastrala, Michael Bennett, Mark M Mitsnefes, Jonathan Barasch, Prasad Devarajan Critical Care 2007, 11:R127 (10 December 2007)

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N-GAL: Diagnosing AKI as soon as possible

Claudio Ronco Critical Care 2007, 11:173 (6 November 2007)

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Prognosis and serum creatinine levels in acute renal failure at the time of nephrology consultation: an observational cohort study

Jose Perez-Valdivieso, Maira Bes-Rastrollo, Pablo Monedero, Jokin de Irala, Francisco Lavilla BMC Nephrology 2007, 8:14 (26 September 2007)

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Acute kidney injury in the intensive care unit: current trends in incidence and outcome

Dinna N Cruz, Claudio Ronco Critical Care 2007, 11:149 (24 July 2007)

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Kidney function assessment in the critically ill child: is it time to leave creatinine behind?

Stuart L Goldstein Critical Care 2007, 11:141 (15 June 2007)

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Acute renal failure in patients with sepsis

José Lopes, Sofia Jorge, Cristina Resina, Carla Santos, Álvaro Pereira, José Neves, Francisco Antunes, Mateus Prata Critical Care 2007, 11:411 (19 April 2007)

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Prognostic utility of RIFLE for acute renal failure in patients with sepsis

José Lopes, Sofia Jorge, Cristina Resina, Carla Santos, Álvaro Pereira, José Neves, Francisco Antunes, Mateus Prata Critical Care 2007, 11:408 (5 April 2007)

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Acute renal failure in obstetrics: risk factors and outcome

Z Haddad, C Kaddour, R Souissi, T Chaaoua, M Laamourou, I Pipien, S Nagi Critical Care 2007, 11(Suppl 2):P385 (22 March 2007)

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Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury

Ravindra L Mehta, John A Kellum, Sudhir V Shah, Bruce A Molitoris, Claudio Ronco, David G Warnock, Adeera Levin, Critical Care 2007, 11:R31 (1 March 2007)

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Acute renal failure in critically ill HIV-infected patients

José Lopes, Joana Fernandes, Sofia Jorge, José Neves, Francisco Antunes, Mateus Prata Critical Care 2007, 11:404 (23 January 2007)

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An assessment of the RIFLE criteria for acute renal failure in critically ill HIV-infected patients

José Lopes, Joana Fernandes, Sofia Jorge, José Neves, Francisco Antunes, Mateus Prata Critical Care 2006, 11:401 (9 January 2007)

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Evidence-based medicine: Classifying the evidence from clinical trials – the need to consider other dimensions

Rinaldo Bellomo, Sean M Bagshaw Critical Care 2006, 10:232 (4 October 2006)

This article is part of a collection on Translational Research

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RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: a cohort analysis

Eric AJ Hoste, Gilles Clermont, Alexander Kersten, Ramesh Venkataraman, Derek C Angus, Dirk De Bacquer, John A Kellum Critical Care 2006, 10:R73 (12 May 2006)

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Arginine-vasopressin in catecholamine-refractory septic versus non-septic shock in extremely low birth weight infants with acute renal injury

Sascha Meyer, Sven Gottschling, Ali Baghai, Donald Wurm, Ludwig Gortner Critical Care 2006, 10:R71 (5 May 2006)

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Patients with ischaemic, mixed and nephrotoxic acute tubular necrosis in the intensive care unit – a homogeneous population?

Wilson JQ Santos, Dirce MT Zanetta, Antonio C Pires, Suzana MA Lobo, Emerson Q Lima, Emmanuel A Burdmann Critical Care 2006, 10:R68 (28 April 2006)

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Solute removal during continuous renal replacement therapy in critically ill patients: convection versus diffusion

Zaccaria Ricci, Claudio Ronco, Alessandra Bachetoni, Giuseppe D'amico, Stefano Rossi, Elisa Alessandri, Monica Rocco, Paolo Pietropaoli Critical Care 2006, 10:R67 (28 April 2006)

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Critical Care – 10 years on

Charlotte Hubbard, Jean-Louis Vincent Critical Care 2006, 10:120 (14 February 2006)

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Prognosis for long-term survival and renal recovery in critically ill patients with severe acute renal failure: a population-based study

Sean M Bagshaw, Kevin B Laupland, Christopher J Doig, Garth Mortis, Gordon H Fick, Melissa Mucenski, Tomas Godinez-Luna, Lawrence W Svenson, Tom Rosenal Critical Care 2005, 9:R700-R709 (25 October 2005)

A year after diagnosis of severe acute renal failure, there is a high mortality rate of 64%, but the prognosis for survivors is good; they are likely to have recovered renal function and become independent of renal replacement therapy.

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Year in review: Critical Care 2004 – nephrology

Zaccaria Ricci, Claudio Ronco Critical Care 2005, 9:523-527 (19 August 2005)

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Clinical review: The meaning of acid–base abnormalities in the intensive care unit part I – epidemiology

Kyle J Gunnerson Critical Care 2005, 9:508-516 (10 August 2005)

This article is part of a collection on Acid base

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Study protocol: The DOse REsponse Multicentre International collaborative initiative (DO-RE-MI)

Detlef Kindgen-Milles, Didier Journois, Roberto Fumagalli, Sergio Vesconi, Javier Maynar, Anibal Marinho, Irene Bolgan, Alessandra Brendolan, Marco Formica, Sergio Livigni, Mariella Maio, Mariano Marchesi, Filippo Mariano, Gianpaola Monti, Elena Moretti, Daniela Silengo, Claudio Ronco Critical Care 2005, 9:R396-R406 (14 June 2005)

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A review of 2004, and with the new year comes a new look

Kerrie Lapworth, Emdadur Rahman, Charlotte Hubbard Critical Care 2005, 9:1-2 (14 January 2005)