Table 2

Regional oxygen-derived variables and portal vein lactate
Parameter
 Baseline
 Minutes after bacterial infusion




15
 90
 120
 150
Mesenteric DO2 (ml/min)
     Control
 71.6 ± 8.5
 37.7 ± 3.9*
 54.4 ± 9.6*
 61.7 ± 10.6
 66.6 ± 11.2
     Lactated Ringer's
 74.3 ± 9.1
 53.5 ± 7.1†
 37.9 ± 5.2†
 47.8 ± 4.2†
 48.2 ± 4.7†
Mesenteric O2ER (%)
     Control
 15.1 ± 1.8
 23.6 ± 3.1*
 32.7 ± 3.7*
 29.7 ± 4.5*
 28.3 ± 3.5*
     Lactated Ringer's
 15.6 ± 2.8
 19.8 ± 2.6†
 27.9 ± 2.8†
 22.3 ± 2.1†
 24.5 ± 2.3†
SpO2 (%)
     Control
 88.3 ± 1.6
 75.9 ± 3.1*
 67.5 ± 3.9*
 71.9 ± 4.8*
 71.7 ± 3.4*
     Lactated Ringer's
 87.9 ± 2.1
 80.2 ± 1.9†
 72.4 ± 3.3†
 80.5 ± 2.1†
 77.4 ± 2.2†
Portal vein lactate (mmol/l)
     Control
 1.56 ± 0.44
 1.67 ± 0.37*
 3.65 ± 0.32*
 3.31 ± 0.35*
 3.32 ± 0.28*
     Lactated Ringer's
 1.58 ± 0.21
 1.88 ± 0.22†
 3.97 ± 0.54†
 4.01 ± 0.52†
 3.55 ± 0.44†
Portal–arterial PCO2 gradient (mmHg)
     Control
 3.6 ± 1.0
 7.9 ± 1.4*
 11.1 ± 1.2*
 9.3 ± 2.1*
 9.6 ± 1.4*
     Lactated Ringer's
 4.9 ± 0.9
 8.7 ± 1.4†
 11.1 ± 1.6†
 6.7 ± 1.7†
 7.5 ± 1.2†

Measurements were taken in control animals (n = 13) and animals treated with lactated Ringer's solution (n = 14). Data are expressed as mean ± standard error of the mean. DO2, oxygen delivery; O2ER, oxygen extraction ratio; PCO2, carbon dioxide tension; SpO2, portal vein oxygen saturation. *P < 0.05, control versus baseline; †P < 0.05 lactated Ringer's versus baseline.

Lagoa et al. Critical Care 2004 8:R221   doi:10.1186/cc2871