|
Clinical and infectious characteristics of all patients with an ICU LOS of more than24 hours |
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| Characteristic |
Center 1 |
Center 2 |
Center 3 |
Center 4 |
Center 5 |
Total |
|
|
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| Enrolled patients (n) |
359 |
146 |
125 |
76 |
178 |
884 |
| Median age (IQR) |
73.6 (58.5–81.5) |
55.4 (42.5–60.6) |
47.6 (32.0–66.9) |
61.4 (44.2–68.7) |
68.9 (57.8–77.1) |
66.4 (49.2–77.1) |
| Male/female (%) |
62/38 |
59/41 |
59/41 |
62/38 |
51/49 |
59/41 |
| Median APACHE II score (IQR) |
16 (11–21) |
17.5 (9.7–25.2) |
16 (12–20) |
16 (10–20) |
18 (14–21) |
17 (11–22) |
| First-day SOFA score (IQR) |
3 (1–5) |
6 (2.7–9) |
6 (3–8) |
4 (2–7) |
6 (4–9) |
4 (2–8) |
| Median ICU LOS, days (IQR) |
3 (2–7) |
5.5 (3–10.2) |
6 (3–12) |
3 (2–7.7) |
4 (2–10) |
4 (2–9) |
| Main ICU admission diagnosis |
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| Respiratory infection, n (%) |
43 (11.9) |
16 (10.9) |
10 (8.0) |
12 (15.8) |
42 (23.6) |
123 (13.9) |
| Acute coronary syndrome, n (%) |
52 (14.5) |
24 (16.4) |
4 (3.2) |
25 (32.9) |
2 (1.1) |
107 (12.0) |
| GI postoperative patients, n (%) |
9 (2.5) |
11 (7.5) |
5 (4.0) |
7 (9.2) |
50 (28.1) |
82 (9.3) |
| Sepsis, n (%) |
34 (9.5) |
2 (1.4) |
17 (13.6) |
3 (3.9) |
13 (7.3) |
69 (7.8) |
| GI surgery for neoplasm, n (%) |
22 (6.1) |
4 (2.7) |
4 (3.2) |
7 (9.2) |
25 (14.0) |
62 (7.0) |
| Cardiovascular surgery, n (%) |
38 (10.6) |
1 (0.06) |
4 (3.2) |
- |
18 (10.1) |
61 (6.9) |
| Clinical neurological disorders, n (%) |
36 (10.0) |
10 (6.8) |
6 (4.8) |
- |
5 (02.8) |
57 (6.4) |
| Site of infection |
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| Lung, n (%) |
86 (72.3) |
30 (43.5) |
52 (67.5) |
24 (68.5) |
75 (70.1) |
267 (65.6) |
| Urinary tract, n (%) |
9 (7.6) |
4 (5.7) |
5 (6.5) |
- |
5 (4.7) |
23 (5.6) |
| Abdomen/surgical wound, n (%) |
4 (3.3) |
5 (7.3) |
- |
5 (14.3) |
6 (5.6) |
20 (4.9) |
| Bloodstream, n (%) |
5 (4.2) |
1 (1.5) |
1 (1.3) |
3 (8.6) |
21 (19.6) |
10 (2.5) |
| Other/unknown, n (%) |
15 (12.6) |
29 (42.2) |
19 (24.7) |
3 (8.6) |
21 (19.6) |
87 (21.4) |
| Diagnosed infections, n (%) |
119 (100) |
69 (100) |
77 (100) |
35 (100) |
107 (100) |
407 (100) |
| Enrolled patients, n |
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| Consensus Conference Diagnosis |
359 |
146 |
125 |
76 |
178 |
884 (100%) |
| SIRS |
291 |
130 |
122 |
74 |
168 |
785 (88.8%) |
| Sepsis |
121 |
72 |
79 |
34 |
109 |
415 (46.9%) |
| Severe sepsis |
57 |
38 |
46 |
191 |
81 |
241 (27.3%) |
| Septic shock |
42 |
34 |
39 |
16 |
72 |
203 (23.0%) |
| Overall mortality rate (%) |
12.5 |
32.2 |
23.7 |
24.8 |
31.4 |
22.3 |
|
GI, gastrointestinal; IQR, interquartile range; LOS, length of stay; SIRS, systemic inflammatory response syndrome; SOFA, sequential organ failure assessment. | ||||||
Silva et al. Critical Care 2004 8:R251 doi:10.1186/cc2892 |
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