|
1999 National projections of severe sepsis by tumor types, adultsa only |
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| Tumor type |
Hospitalizationsb |
No severe sepsis mortality |
Severe sepsis cases |
Severe sepsis mortality |
Severe sepsis ratec |
Relative risk of severe sepsisd(confidence interval) |
|
|
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| Noncancer |
||||||
| Total patientse |
22,651,429 |
2.0 |
790,743 |
24.9 |
4.2 |
1.00 |
| Cancer |
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| Total patientse |
2,531,994 |
7.1 |
126,209 |
37.8 |
16.4 |
3.96 (3.94 – 3.99) |
| Hematologic tumor |
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| Non-Hodgkins lymphoma |
159,984 |
5.9 |
11,729 |
40.4 |
43.4 |
10.26 (10.08–10.44) |
| Lymphocytic leukemia |
60,365 |
5.9 |
6447 |
32.8 |
77.8 |
18.40 (17.97–18.84) |
| Hodgkin's disease |
20,617 |
3.3 |
1,575 |
38.0 |
17.2 |
4.07 (3.87–4.27) |
| Multiple myeloma |
69,576 |
6.1 |
6588 |
32.2 |
142.2 |
33.61 (32.87–34.38) |
| Myeloid leukemia |
53,523 |
9.7 |
8234 |
35.2 |
275.5 |
65.15 (63.95–66.36) |
| Monocytic leukemia |
949 |
14.5 |
110 |
45.8 |
108.3 |
25.62 (21.5–30.6) |
| Total hematologic tumor |
365,014 |
6.3 |
34,684 |
36.1 |
66.4 |
15.71 (15.55–15.88) |
| Solid tumors |
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| Breast cancer |
197,808 |
3.1 |
2915 |
34.6 |
1.6 |
0.39 (0.38–0.4) |
| Prostate cancer |
225,789 |
3.5 |
6883 |
27.5 |
4.8 |
1.13 (1.1–1.16) |
| Colon and rectum cancer |
232,423 |
5.1 |
9409 |
35.8 |
9.8 |
2.32 (2.27–2.37) |
| Urinary bladder cancer |
85,256 |
3.6 |
3176 |
27.8 |
7.1 |
1.67 (1.61–1.73) |
| Skin melanoma |
14,203 |
4.9 |
200 |
38.1 |
0.5 |
0.11 (0.1–0.13) |
| Corpus and uterus cancer |
51,212 |
2.2 |
1002 |
27.1 |
2.4 |
0.57 (0.53–0.6) |
| Lung and bronchus cancer |
359,236 |
12.0 |
20,377 |
45.2 |
58.2 |
13.76 (13.58–13.95) |
| Thyroid cancer |
27,467 |
1.1 |
178 |
32.4 |
0.9 |
0.21 (0.18–0.24) |
| Kidney and renal pelvis cancer |
45,656 |
4.8 |
1510 |
28.0 |
8.8 |
2.07 (1.97–2.18) |
| Ovary cancer |
57,315 |
5.1 |
1682 |
33.3 |
10.8 |
2.56 (2.44–2.68) |
| Brain and other nervous cancer |
43,096 |
6.0 |
1512 |
28.2 |
27.5 |
6.50 (6.18–6.83) |
| Total solid tumors |
1,339,463 |
6.1 |
48,846 |
37.2 |
7.6 |
1.81 (1.79–1.82) |
|
aAdults defined as aged > 20 years. bAfter adjusting for age and gender, cancer patients are much more likely to be hospitalized (relative risk, 2.77; 95% confidence interval, 2.773–2.779) and to be hospitalized with severe sepsis (relative risk, 3.96; 95% confidence interval, 3.94–3.99). cSevere sepsis cases per 1000 population. dRelative risk of severe sepsis between tumor type and noncancer population (excluding childbirth). eChildbirth-related discharges not included. | ||||||
Williams et al. Critical Care 2004 8:R291 doi:10.1186/cc2893 |
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