Table 1

Biological processes identified by MAPPFinder based on gene expression
GOID
 GO Name
 Number of changed genes
 Number of measured genes
 Number of genes in GO
 Percentage changed genes
 Percentage present genes
 Z score
7596
 Blood coagulation
 8
 26
 74
 30.77
 35.14
 3.56
6954
 Inflammatory response
 13
 44
 168
 29.55
 26.19
 4.35
8285
 Negative regulation of cell proliferation
 8
 32
 129
 25.00
 24.81
 2.88
6935
 Chemotaxis
 7
 31
 107
 22.58
 28.97
 2.28
6955
 Immune response
 13
 61
 569
 21.31
 10.72
 4.17

The bioprocesses affected by mechanical stretch were identified using MAPPFinder [12] software, designed by the BayGenomics PGA group for dynamic linkage of gene expression data to the Gene Ontology (GO; http://www.geneontology.org webcite hierarchy. Data were filtered by number of changed genes (> 5) and Z score (> 2.0) and sorted by percentage changed genes.

Grigoryev et al. Critical Care 2004 8:440   doi:10.1186/cc2901