Table 1

Biological processes identified by MAPPFinder based on gene expression

GOID
GO Name
Number of changed genes
Number of measured genes
Number of genes in GO
Percentage changed genes
Percentage present genes
Z score

7596
Blood coagulation
8
26
74
30.77
35.14
3.56
6954
Inflammatory response
13
44
168
29.55
26.19
4.35
8285
Negative regulation of cell proliferation
8
32
129
25.00
24.81
2.88
6935
Chemotaxis
7
31
107
22.58
28.97
2.28
6955
Immune response
13
61
569
21.31
10.72
4.17

The bioprocesses affected by mechanical stretch were identified using MAPPFinder [12] software, designed by the BayGenomics PGA group for dynamic linkage of gene expression data to the Gene Ontology (GO; http://www.geneontology.org hierarchy. Data were filtered by number of changed genes (> 5) and Z score (> 2.0) and sorted by percentage changed genes.

Grigoryev et al. Critical Care 2004 8:440   doi:10.1186/cc2901