Table 2

Gas exchange during acute lung injury in sheep

Parameter
Group
Time point (hours)





0
2
4
6

pHa
Sham
7.52 ± 0.03
7.53 ± 0.02
7.50 ± 0.02
7.50 ± 0.02

LPS
7.48 ± 0.01
7.50 ± 0.02
7.55 ± 0.02*
7.53 ± 0.02

OA
7.50 ± 0.01
7.44 ± 0.03
-
-
PaCO2 (mmHg)
Sham
38.7 ± 2.7
36.4 ± 2.1
36.4 ± 1.6
37.4 ± 1.0

LPS
39.7 ± 1.4
38.8 ± 1.5
32.6 ± 0.6*
33.1 ± 1.0*

OA
36.4 ± 1.1
42.5 ± 3.7
-
-
Haemoglobin (g/dl)
Sham
10.7 ± 0.9
10.1 ± 0.6
10.2 ± 0.5
10.3 ± 0.5

LPS
10.4 ± 0.6
10.4 ± 0.6
11.0 ± 0.7*
10.9 ± 0.6

OA
10.3 ± 0.4
10.7 ± 0.5
-
-
Blood temperature (°C)
Sham
39.3 ± 0.1
39.2 ± 0.1
39.3 ± 0.1
39.3 ± 0.1

LPS
39.3 ± 0.1
40.0 ± 0.1*
41.3 ± 0.1*
41.0 ± 0.1*

OA
39.5 ± 0.1
39.6 ± 0.1
-
-

Data are expressed as means ± standard error of the mean. *P < 0.05, versus t = 0 hours in LPS group; P < 0.05, OA versus sham operated group; P < 0.05, LPS versus sham-operated group. LPS, lipopolysaccharide; OA, oleic acid; PaCO2, arterial carbon dioxide tension; Sham, sham-operated.

Kirov et al. Critical Care 2004 8:R451   doi:10.1186/cc2974