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Numbers of lambs undergoing various resuscitative measures |
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| Type of support |
Group |
Pa |
|
|
|
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| CMV (n = 8) |
AV-ECMO (n = 9) |
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|
|
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| Lactated Ringer's (10 ml/kg) |
2 |
8 |
0.015 |
| Epinephrine (0.5–2 μg/kg per min) |
1 |
6 |
0.049 |
| Dopamine (5 μg/kg per min) |
1 |
6 |
0.049 |
| Bicarbonate (1 mEq/kg bolus) |
1 |
6 |
0.049 |
| Surviving/nonsurviving |
6/2 |
4/5 |
0.333 |
| Total number of resuscitative measures in surviving lambs |
2 (n = 6) |
12 (n = 4) |
0.001 |
| Cause of death |
Prolonged hypotension with MAP <30 mmHg |
Prolonged hypotension with MAP <30 mmHg and AV shunt <5% of CO |
|
|
Comparison of various resuscitative measures after acute lung injury in surviving and nonsurviving lambs subjected to conventional mechanical ventilation (CMV) with closed arteriovenous (AV) shunt or CMV with AV-extracorporeal membrane oxygenation (ECMO) using up to 15% AV shunt. aP values derived using Fisher's exact test. CO, cardfiac output; MAP, mean arterial pressure. | |||
Totapally et al. Critical Care 2004 8:R495 doi:10.1186/cc2983 |
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