Critical Care

official impact factor 4.60

Commentary

Another piece in the puzzle

Thomas S Maxey1* and William B Keeling2

Author Affiliations

1 Chief Resident, General Surgery, Department of Surgery, University of South Florida College of Medicine, Tampa, Florida, USA

2 Senior Resident, General Surgery, Department of Surgery, University of South Florida College of Medicine, Tampa, Florida, USA

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Critical Care 2005, 9:27-28 doi:10.1186/cc3019

Published: 9 December 2004

Abstract

Pulmonary ischemia–reperfusion injury is complex and involves many cell types and mechanisms of action. Van Putte and coworkers have attempted to provide insight into and describe some of the complex components of this process. Their study describes two new components of the multifaceted process of reperfusion injury. The time-dependent course of neutrophil activation and the discovery of programmed cell death in reperfused lung tissue are two new pieces of a complex puzzle.

Keywords:
ischemia–reperfusion injury; lung injury; pulmonary