Table 1

Summary of studies of dantrolene treatment of heat stroke in humans



Numbers included








Reference
 Study type
 Setting
 Dantrolene treatment arms
 Control arms
 Dantrolene dose (mg/kg bw)
 Improved parameters
 Nonimproved parameters
[21]
 Randomized, double-blind, controlled
 Patients with classic heat stroke
 26
 26
 2
 -
 Cooling rate, mean number of hospital stays
[17]
 Randomized controlled
 Heat stroke patient
 8
 12
 2–4
 Cooling rate
 Survival, neurological sequelae

bw, Body weight.

Hadad et al. Critical Care 2005 9:86   doi:10.1186/cc2923