Table 1

Baseline demographic characteristics and outcomes for all patients with severe sepsis

ARDS
 Non-ARDS
 Total
Patients (n)
 15
 14
 29
Baseline characteristics
     Age (years)
 44 ± 12
 57 ± 14
 51 ± 15*
     Sex (male)
 5/15
 5/14
 10/29
     Race (African American/Caucasian/other)
 12/3/0
 12/0/2
 24/3/2
     Chronic heart disease
 1/15
 2/14
 3/29
     Chronic obstructive lung disease
 1/15
 1/15
 2/29
     Chronic renal disease (serum creatinine ≥ 2.0 mg/dl)
 1/15
 3/14
 4/29
     HIV infection
 7/15
 4/14
 11/29
     Chronic alcohol abuse
 5/15
 8/14
 13/29
     Bacteremia
 7/15
 5/14
 12/29
     APACHE II score (day 1)
 23.9 ± 6.5
 27.7 ± 8.3
 25.7 ± 7.5
     Mechanically ventilated
 14/15
 11/14
 25/29
Physiology at enrollment
     White blood cell count (cells × 103/ml)
 20.4 (10.8–30.0)
 13.6 (3.8–23.4)
 17.2 (8.9–25.5)
     Prior 24-hour fluid balance (ml)
 2506 ± 2583
 4993 ± 3625
 3523 ± 3223
     Shock (vasopressor requirement)
 12/15
 10/14
 22/29
     Cardiac index (l/min per m2)
 3.8 ± 1.0
 4.3 ± 1.4
 4.0 ± 1.2
     GEDV index (ml/m2)
 648 ± 184
 719 ± 119
 681 ± 159
     SVRI (dyn·s/cm5 per m2)
 1408 ± 441
 1668 ± 669
 1528 ± 562
     EVLW index (ml/kg)
 15.0 (9.0–16.7)
 7.0 (5.0–8.2)
 8.5 (5.1–15.8)*
Outcome
     ICU length of stay (days)
 14.0 (8.5–21.0)
 10.0 (4.8–16.3)
 13.0 (7.0–17.0)
     Hospital length of stay (days)
 26.0 (12.3–42.3)
 19.0 (16.0–31.0)
 19.0 (13.0–36.0)
     28-day mortality
 7/15
 5/14
 12/29

Values are expressed as mean ± standard deviation, frequency (%), or median (interquartile range), unless otherwise noted.

* P for difference between groups < 0.05. APACHE, Acute Physiology and Chronic Health Evaluation; ARDS, acute respiratory distress syndrome; EVLW, extravascular lung water; GEDV, global end-diastolic volume; ICU, intensive care unit; SVRI, systemic vascular resistance index.

Martin et al. Critical Care 2005 9:R74   doi:10.1186/cc3025