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Demographics, baseline patient characteristics and outcomes of ARDS and non-ARDS patients stratified by lung water content |
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| Non-ARDS |
ARDS |
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|
|
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| Low EVLW (n = 6) |
High EVLW (n = 8) |
P |
Low EVLW (n = 4) |
High EVLW (n = 11) |
P |
|
|
|
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| EVLW (ml/kg) |
5.0 (4.8–8.1) |
7.7 (5.0–8.7) |
NS |
9.0 (8.0–9.8) |
16.0 (13.0–20.3) |
0.07 |
| Source (n [% pulmonary]) |
2/6 (33%) |
3/8 (38%) |
NS |
3/4 (75%) |
8/11 (73%) |
NS |
| APACHE II score |
27.8 ± 2.3 |
27.6 ± 11.6 |
NS |
18.5 ± 3.3 |
25.9 ± 6.3 |
0.05 |
| PaO2/FiO2 index (mmHg) |
424.0 ± 51.7 |
244.3 ± 133.9 |
0.02 |
91.5 ± 24.6 |
144.9 ± 89.9 |
NS |
| LIS |
0.8 ± 0.2 |
0.9 ± 0.9 |
NS |
2.6 ± 1.7 |
2.7 ± 1.1 |
NS |
| CXR score |
0.5 (0–1) |
1 (0–2) |
NS |
3 (2–4) |
4 (3–4) |
NS |
| GEDV index (ml/m2) |
750.5 ± 133.6 |
691.3 ± 108.1 |
NS |
581.5 ± 131.4 |
671.8 ± 200.0 |
NS |
| Fluid balance (prior 24 hours; ml) |
5256 ± 4918 |
4664 ± 1591 |
NS |
2373 ± 776 |
2545 ± 2959 |
NS |
| Chronic alcohol abuse (n [%]) |
4/6 (67%) |
4/8 (50%) |
NS |
0/4 (0%) |
5/11 (45%) |
0.09 |
| 28-Day mortality (n [%]) |
1/6 (17%) |
4/8 (50%) |
0.20 |
0/4 (0%) |
7/11 (64%) |
0.03 |
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Extravascular lung water (EVLW), Acute Physiology and Chronic Health Evaluation (APACHE) II, arterial oxygen tension (PaO2)/fractional inspired oxygen (FiO2) ratio, Lung Injury Score (LIS), and chest radiographic (CXR) score are initial values calculated from study day 1. Values are expressed as means ± standard deviation or as median (interquartile range). ARDS, acute respiratory distress syndrome. | ||||||
Martin et al. Critical Care 2005 9:R74 doi:10.1186/cc3025 |
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