|
Demographics, baseline patient characteristics and outcomes of ARDS and non-ARDS patients stratified by history of chronic alcohol abuse |
||||||
| Non-ARDS |
ARDS |
|||||
|
|
||||||
| Chronic alcohol abuse (n = 8) |
Nonalcoholic (n = 6) |
P |
Chronic alcohol abuse (n = 8) |
Nonalcoholic (n = 6) |
P |
|
|
|
||||||
| EVLW (ml/kg) |
7.0 (5.0–8.0) |
6.5 (4.8–8.8) |
NS |
20.3 (16.0–26.7) |
9.5 (7.1–15.4) |
0.009 |
| Source (n [% pulmonary]) |
2/8 (25%) |
1/6 (17%) |
NS |
5/5 (100%) |
7/10 (70%) |
0.17 |
| APACHE II score |
28.7 ± 9.3 |
26.5 ± 7.7 |
NS |
27.0 ± 6.7 |
22.4 ± 6.1 |
NS |
| PaO2/FiO2 index (mmHg) |
369.7 ± 140.8 |
215.7 ± 116.7 |
NS |
96.7 ± 21.7 |
148.0 ± 95.1 |
NS |
| LIS |
0.9 ± 0.6 |
0.8 ± 0.7 |
NS |
3.2 ± 0.5 |
2.4 ± 1.4 |
NS |
| CXR score |
0.5 (0.0–1.3) |
1.0 (0.5–1.5) |
NS |
4.0 (2.5–4.0) |
3.5 (2.5–4.0) |
NS |
| GEDV index (ml/m2) |
750.3 ± 142.7 |
681.7 ± 81.6 |
NS |
714.7 ± 149.7 |
614.2 ± 197.9 |
NS |
| Fluid balance (prior 24 hours; ml) |
4703 ± 3310 |
6004 ± 6064 |
NS |
4758 ± 3240 |
1504 ± 1550 |
0.03 |
| 28-Day mortality (n [%]) |
4/8 (50%) |
1/6 (17%) |
0.19 |
3/5 (60%) |
4/10 (40%) |
NS |
|
Extravascular lung water (EVLW), Acute Physiology and Chronic Health Evaluation (APACHE) II, arterial oxygen tension (PaO2)/fractional inspired oxygen (FiO2) ratio, Lung Injury Score (LIS), and chest radiographic (CXR) score are initial values calculated from study day 1. Values are expressed as means ± standard deviation or as median (interquartile range). ARDS, acute respiratory distress syndrome. | ||||||
Martin et al. Critical Care 2005 9:R74 doi:10.1186/cc3025 |
||||||