Critical Care

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Decreased duration of mechanical ventilation when comparing analgesia-based sedation using remifentanil with standard hypnotic-based sedation for up to 10 days in intensive care unit patients: a randomised trial [ISRCTN47583497]

Des Breen1*, Andreas Karabinis2, Manu Malbrain3, Rex Morais4, Sven Albrecht5, Inge-Lise Jarnvig6, Pauline Parkinson7 and Andrew JT Kirkham8

Author Affiliations

1 Consultant in Anaesthesia and Intensive Care, Royal Hallamshire Hospital, Sheffield, UK

2 Director of Intensive Care Unit, Genimatas General Hospital, Athens, Greece

3 Director of Intensive Care Unit, ZiekenhuisNetwerk Antwerpen, Antwerpen, Belgium

4 Consultant Anaesthetist, Intensive Care Unit, Dubai Hospital, Dubai, United Arab Emirates

5 Deputy Director, Universität Erlangen-Nürnberg, Klinik für Anästhesiologie, Erlangen, Germany

6 Senior Registrar, Intensive Care Unit, Righospitalet, Copenhagan, Denmark

7 Clinical Scientist, Neurosciences Medicines Development Centre, GlaxoSmithKline, Greenford, Middlesex, UK

8 Clinical Development Director, Neurosciences Medicines Development Centre, GlaxoSmithKline, Greenford, Middlesex, UK

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Critical Care 2005, 9:R200-R210 doi:10.1186/cc3495


See related commentary http://ccforum.com/content/9/3/247

Published: 15 March 2005

Additional files

Additional File 1:

A Word file showing the definitions of the scores on the Sedation–Agitation Scale.

Format: DOC Size: 21KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data

Additional File 2:

A Word file showing the definitions of pain intensity scores.

Format: DOC Size: 19KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data