Table 2

Identification of Lactobacillus plantarum 299v (Lp 299v) from biopsies and the antibiotics used

Patient

Lp 299v, first biopsy

Lp 299v, later biopsies

Antibiotics prior to ICU admission (≤ 12 days if not specified)

Antibiotics in ICU before first biopsy

Antibiotics in ICU (during biopsy period)


Treatment group

2

No

Yes

Erythromycin

Erythromycin + imipenem

Erythromycin + imipenem

4

No

No

Cefuroxime

Cefuroxime

1 Imipenem, 2 +metronidazol

5

No

No

Cefadroxile, 10 days

Cefadroxile

1 Cefuroxime, 2 meropenem

10

No

No

Cefuroxime, 3 days

Imipenem

1 Imipenem, 2 +metronidazol

12

No

No

No antibiotics

Imipenem

Imipenem

14

No

Yes

1 Metronidazol + cefotaxime/cefuroxime, 2 -metronidazol, 3 -cefotaxime/cefuroxime; + imipenem; 12 days in total

Imipenem

Imipenem

15

No

Yes

Ciprofloxacin + two doses metronidazol (rectally)

Ceftazidime

1 Ceftazidime, 2 +metronidazol

17

No

No

Cefuroxime

Imipenem

Imipenem

Control group

1

No

No

Cloxacillin

1 Cloxacillin, 2 cefuroxime

1 Cefuroxime, 2 +metronidazol

3

Yes

No

Imipenem

Imipenem

1 Imipenem, 2 +metronidazol

6

Yes

No

1 Penicillin G, 2 erythromycin, 3 +netilmicin, 4 cefotaxime (-netilmicin, -erythromycin), 5 erythromycin, 6 imipenem; 3 weeks in total

Imipenem

Imipenem

8

Yes

No

Penicillin G

Imipenem

1 Imipenem, 2 +clindamycin, 3 -clindamycin, +metronidazol, 4 vancomycin+ ciprofloxacin

11

No

No

Metronidazol and cefuroxime

Metronidazol and cefuroxime

1 metronidazol + cefuroxime, 2 +isoniazid, 3 +rifampicin, 4 -(1, 2, 3), +imipenem

13

Yes

No

1 PenicillinV, 2 cefuroxime; 6 days in total

Cefuroxime

Cefuroxime

16

No

No

Cefuroxime

Cefuroxime

1 Cefuroxime, 2 penicillin G


Figures indicate the order in which antibiotics were been given (and changed). +, added medication; -, withdrawn medication. ICU, intensive care unit.

Klarin et al. Critical Care 2005 9:R285-R293   doi:10.1186/cc3522

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