Table 2

Clinical variables before and after administration of recombinant human DNase

Variable
Before
After
P

Heart rate (beats/min)
150 (121–164)
130 (115–145)
0.06
Respiratory rate
41 (26–60)
36 (25–40)
0.01
PCO2 (kPa)
6.55 (5.7–8.6)
6.00 (5.3–7.5)
0.005
FiO2 (%)
50 (40–100)
40 (21–75)
<0.001
Chest X-ray score
4 (2–6)
2 (0–4)
<0.001

Data presented as the median (interquartile range). Comparisons were made using the Wilcoxon signed rank test.

Hendriks et al. Critical Care 2005 9:R351   doi:10.1186/cc3544