Table 1

Patient characteristics and hemostatic variables before antithrombin substitution

Patient no.

Diagnosis

Organism

Age (years)

APACHE II score

PT (%)

aPTT (sec)

Fibrinogen (mg/dl)

AT (%)

D-dimer (μg/l)

Thrombocyte count

Outcome

1

Pneumonia, SBP

Staphylococcus aureus

56

38

30

73

263

20

2,374

47,000

Died

2

Pneumonia, SBP

Staphylococcus aureus

31

43

18

58

198

23

2,177

24,000

Died

3

SBP

No organism

56

39

37

51

266

39

976

38,000

Survived

4

Pneumonia

Fusobacterium necrophorum

19

35

71

56

490

36

999

55,000

Survived

5

Pneumonia

Streptococcus pneumoniae

50

28

37

77

290

34

6,500

89,000

Survived

6

Pneumonia, AML

Klebsiella sp.

61

30

45

45

80

53

6,500

87,000

Died

7^a

Pneumonia, AML

Escherichia coli

62

32

60

50

690

34

1,368

11,000

Survived

8^a

Pneumonia

Staphylococcus epidermidis

21

27

52

54

602

36

1,291

31,000

Survived

^aPatients who received concomitant low-dose heparin. AT, antithrombin; aPTT, activated partial thromboplastin time; PT, prothrombin time. SBP = spontaneous bacterial peritonitis, AML = acute myelogenous leukemia

Kountchev et al. Critical Care 2005 9:R596   doi:10.1186/cc3808