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Likelihood of death or ICU admission by comorbidity for patients with severe sepsis |
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| Comorbidity |
Adjusted odds ratio for mortalitya (95% confidence interval) |
Adjusted odds ratio for ICU admissionb (95% confidence interval) |
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| Only HIV/AIDS |
Reference group |
Reference group |
| No comorbidity |
0.36 (0.33–0.39) |
1.85 (1.70–2.01) |
| Only diabetes |
0.37 (0.33–0.42) |
1.82 (1.66–2.00) |
| Only pulmonary disease |
0.38 (0.33–0.43) |
1.93 (1.71–2.18) |
| Only cardiovascular disease |
0.39 (0.33–0.47) |
1.93 (1.66–2.24) |
| Only renal disease |
0.67 (0.56–0.80) |
1.76 (1.52–2.04) |
| Only liver disease |
1.28 (1.14–1.44) |
2.40 (2.16–2.67) |
| Only neoplasm |
1.79 (1.61–1.98) |
1.62 (1.48–1.79) |
| HIV with other comorbid illness(es) |
1.67 (1.47–1.90) |
1.07 (0.95–1.22) |
| Multiple comorbid illnesses without HIV/AIDS |
0.99 (0.89–1.10) |
1.75 (1.59–1.93) |
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aAdjusted for intensive care unit (ICU) admission, age, gender, race, infection site, payer, failing organ systems, presence of opportunistic infection, and hospital teaching status (c-statistic = 0.80). bAdjusted for mortality, age, gender, race, infection site, payer, failing organ systems, presence of opportunistic infection, and hospital teaching status (c-statistic = 0.79). | ||
Mrus et al. Critical Care 2005 9:R623 doi:10.1186/cc3811 |
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