Table 3

Likelihood of death or ICU admission by comorbidity for patients with severe sepsis

Comorbidity

Adjusted odds ratio for mortality^a (95% confidence interval)

Adjusted odds ratio for ICU admission^b (95% confidence interval)

Only HIV/AIDS

Reference group

Reference group

No comorbidity

0.36 (0.33–0.39)

1.85 (1.70–2.01)

Only diabetes

0.37 (0.33–0.42)

1.82 (1.66–2.00)

Only pulmonary disease

0.38 (0.33–0.43)

1.93 (1.71–2.18)

Only cardiovascular disease

0.39 (0.33–0.47)

1.93 (1.66–2.24)

Only renal disease

0.67 (0.56–0.80)

1.76 (1.52–2.04)

Only liver disease

1.28 (1.14–1.44)

2.40 (2.16–2.67)

Only neoplasm

1.79 (1.61–1.98)

1.62 (1.48–1.79)

HIV with other comorbid illness(es)

1.67 (1.47–1.90)

1.07 (0.95–1.22)

Multiple comorbid illnesses without HIV/AIDS

0.99 (0.89–1.10)

1.75 (1.59–1.93)

^aAdjusted for intensive care unit (ICU) admission, age, gender, race, infection site, payer, failing organ systems, presence of opportunistic infection, and hospital teaching status (c-statistic = 0.80). ^bAdjusted for mortality, age, gender, race, infection site, payer, failing organ systems, presence of opportunistic infection, and hospital teaching status (c-statistic = 0.79).

Mrus et al. Critical Care 2005 9:R623   doi:10.1186/cc3811