Early goal-directed therapy after major surgery reduces complications and duration of hospital stay. A randomised, controlled trial [ISRCTN38797445]
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* Corresponding author: Rupert Pearse rupert.pearse@doctors.net.uk
Critical Care 2005, 9:R687-R693 doi:10.1186/cc3887
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BioMed Central: 37 citations
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Research
Brian H Cuthbertson, Marion K Campbell, Stephen A Stott, Andrew Elders, Rodolfo Hernández, Dwayne Boyers, John Norrie, John Kinsella, Julie Brittenden, Jonathan Cook, Daniela Rae, Seonaidh C Cotton, David Alcorn, Jennifer Addison, Adrian Grant, Critical Care 2011, 15:R296 (16 December 2011) |
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Research
Joseph Rinehart, Brenton Alexander, Yannick Manach, Christoph Hofer, Benoit Tavernier, Zeev N Kain, Maxime Cannesson Critical Care 2011, 15:R278 (23 November 2011) |
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Review
Clinical review: use of venous oxygen saturations as a goal - a yet unfinished puzzle Paul van Beest, Götz Wietasch, Thomas Scheeren, Peter Spronk, Michaël Kuiper Critical Care 2011, 15:232 (24 October 2011) |
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Study protocol
Matthew D Wiles, William JD Whiteley, Chris G Moran, Iain K Moppett Trials 2011, 12:213 (28 September 2011) |
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Research
Suzana M Lobo, Luis S Ronchi, Neymar E Oliveira, Paulo G Brandão, Adriano Froes, Geni S Cunrath, Kátia G Nishiyama, João G Netinho, Francisco R Lobo Critical Care 2011, 15:R226 (23 September 2011) |
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Review
Clinical applicability of functional hemodynamic monitoring Xaime García, Michael R Pinsky Annals of Intensive Care 2011, 1:35 (25 August 2011) |
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Research article
Frederik J van der Sluis, Cornelis Slagt, Barbara Liebman, Jan Beute, Jan WR Mulder, Alexander F Engel BMC Surgery 2011, 11:18 (23 August 2011) |
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Research
Maxime Cannesson, Gunther Pestel, Cameron Ricks, Andreas Hoeft, Azriel Perel Critical Care 2011, 15:R197 (15 August 2011) |
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Research
Jukka Takala, Esko Ruokonen, Jyrki J Tenhunen, Ilkka Parviainen, Stephan M Jakob Critical Care 2011, 15:R148 (15 June 2011) |
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Research
Goal-directed haemodynamic therapy during elective total hip arthroplasty under regional anaesthesia Maurizio Cecconi, Nicola Fasano, Nicola Langiano, Michele Divella, Maria G Costa, Andrew Rhodes, Giorgio Rocca Critical Care 2011, 15:R132 (30 May 2011) |
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Review
Cardiac output monitoring: an integrative perspective Jamal A Alhashemi, Maurizio Cecconi, Christoph K Hofer Critical Care 2011, 15:214 (22 March 2011) This article is part of a collection on Selected articles from the... |
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Research
Mehrnaz Hadian, Hyung Kook Kim, Donald A Severyn, Michael R Pinsky Critical Care 2010, 14:R212 (23 November 2010) |
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Commentary
Inotropes in goal-directed therapy: Do we need 'goals'? Emmanuel Futier, Benoit Vallet Critical Care 2010, 14:1001 (29 September 2010) |
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Research
Shaman Jhanji, Amanda Vivian-Smith, Susana Lucena-Amaro, David Watson, Charles J Hinds, Rupert M Pearse Critical Care 2010, 14:R151 (10 August 2010) |
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Commentary
Improving surgical outcomes: it is the destination not the journey Jonathan Wilson, Simon Davies Critical Care 2010, 14:177 (16 July 2010) |
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Commentary
Pulse pressure analysis: to make a long story short Maurizio Cecconi, Andrew Rhodes Critical Care 2010, 14:175 (12 July 2010) |
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Research
Jan Benes, Ivan Chytra, Pavel Altmann, Marek Hluchy, Eduard Kasal, Roman Svitak, Richard Pradl, Martin Stepan Critical Care 2010, 14:R118 (16 June 2010) |
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Commentary
Goal-directed or goal-misdirected - how should we interpret the literature? Anthony M Roche, Timothy E Miller Critical Care 2010, 14:129 (10 March 2010) |
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Review
Choosing patient-tailored hemodynamic monitoring Cornelis Slagt, Rose-Marieke BGE Breukers, AB Johan Groeneveld Critical Care 2010, 14:208 (9 March 2010) This article is part of a collection on Selected articles from the... |
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Poster presentation
M Costa, T Cecconet, P Chiarandini, L Pompei, S Tomasino, S Buttera, G Della Rocca Critical Care 2010, 14(Suppl 1):P111 (1 March 2010) |
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Research
Jochen Mayer, Joachim Boldt, Andinet M Mengistu, Kerstin D Röhm, Stefan Suttner Critical Care 2010, 14:R18 (15 February 2010) |
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Review
Clinical review: Goal-directed therapy in high risk surgical patients Nicholas Lees, Mark Hamilton, Andrew Rhodes Critical Care 2009, 13:231 (26 October 2009) |
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Research
Crystalloids versus colloids for goal-directed fluid therapy in major surgery Luzius B Hiltebrand, Oliver Kimberger, Michael Arnberger, Sebastian Brandt, Andrea Kurz, Gisli H Sigurdsson Critical Care 2009, 13:R40 (21 March 2009) |
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Poster presentation
Fluid responsiveness in patients following major surgery M Tuccillo, M Cecconi, N Al-Subaie, M Hamilton, R Grounds, G Della Rocca, A Rhodes Critical Care 2009, 13(Suppl 1):P214 (13 March 2009) |
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Review
Maurizio Cecconi, Andrew Rhodes, Jan Poloniecki, Giorgio Della Rocca, R Michael Grounds Critical Care 2009, 13:201 (13 January 2009) |
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Research
Tim C Jansen, Jasper van Bommel, Paul G Mulder, Johannes H Rommes, Selma JM Schieveld, Jan Bakker Critical Care 2008, 12:R160 (17 December 2008) In a cohort of patients that required urgent ambulance dispatching, pre-hospital blood lactate levels were associated with in-hospital mortality and provided prognostic information superior to patient vital signs.
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Research
Marcel R Lopes, Marcos A Oliveira, Vanessa Pereira, Ivaneide Lemos, Jose Auler, Frédéric Michard Critical Care 2007, 11:R100 (7 September 2007) Monitoring and minimising arterial pulse pressure variation by volume loading during high-risk surgery improved post-operative outcome and decreased length of hospital stay, in a pilot randomised controlled trial.
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Commentary
Caudwell Xtreme Everest: a field study of human adaptation to hypoxia Mike Grocott, Alan Richardson, Hugh Montgomery, Monty Mythen Critical Care 2007, 11:151 (1 August 2007) |
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Poster presentation
M Hamilton, M Canete, M Cecconi, N Al-subaie, A Vercuil, J Fawcett, D Dawson, A Rhodes Critical Care 2007, 11(Suppl 2):P271 (22 March 2007) |
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Research article
The incidence of myocardial injury following post-operative Goal Directed Therapy Rupert M Pearse, Deborah Dawson, Jayne Fawcett, Andrew Rhodes, R Michael Grounds, David Bennett BMC Cardiovascular Disorders 2007, 7:10 (19 March 2007) |
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Research
Ivan Chytra, Richard Pradl, Roman Bosman, Petr Pelnář, Eduard Kasal, Alexandra Židková Critical Care 2007, 11:R24 (22 February 2007) Optimization of intravascular volume using esophageal Doppler in multiple trauma patients is associated with a decrease of blood lactate levels, lower incidence of infectious complications and reduced duration of hospital stay.
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Commentary
Should we use central venous saturation to guide management in high-risk surgical patients? Rupert M Pearse, Charles J Hinds Critical Care 2006, 10:181 (15 December 2006) |
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Review
Year in review 2005: Critical Care – cardiology Timothy Gatheral, E David Bennett Critical Care 2006, 10:225 (15 August 2006) |
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Research
Identification and characterisation of the high-risk surgical population in the United Kingdom Rupert M Pearse, David A Harrison, Philip James, David Watson, Charles Hinds, Andrew Rhodes, R Michael Grounds, E David Bennett Critical Care 2006, 10:R81 (2 June 2006) Despite more than 80% of postoperative deaths occurring in high-risk surgical patients, only 15% are admitted to the intensive care unit, suggesting inadequate provision of critical care resources.
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Commentary
Advances in protocolising management of high risk surgical patients E David Bennett Critical Care 2006, 10:124 (20 February 2006) |
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Commentary
Hemodynamic monitoring over the past 10 years Michael R Pinsky Critical Care 2006, 10:117 (9 February 2006) |