Table 1

Baseline characteristics of patients in the goal-directed therapy (GDT) and control groups

Characteristics
Control group
GDT group

Number in group
60
62
Age (years)
68 ± 11.6
66 ± 11.4
Male
39 (65%)
42 (68%)
P-POSSUM operative score
17.1 ± 4.9
17.8 ± 4.9
P-POSSUM physiology score
19.8 ± 5.5
21.9 ± 6.7
APACHE II score
9.6 ± 4.3
9.4 ± 3.9
ASA status 3 and above
43 (72%)
50 (81%)
Aged over 70 years with limited physiological reserve
20 (33%)
13 (21%)
Known history of severe cardiac or respiratory illness
22 (37%)
19 (31%)
Extensive surgery planned for carcinoma involving bowel anastomosis
21 (35%)
27 (44%)
Late-stage vascular disease involving the aorta
15 (25%)
11 (18%)
Elective surgery
54 (90%)
55 (88%)
Type of surgery


     Vascular
16 (27%)
12 (19%)
     Upper gastro-intestinal
8 (13%)
16 (26%)
     Hepato-biliary
4 (7%)
8 (13%)
     Lower gastro-intestinal
14 (23%)
10 (16%)
     Urology
15 (25%)
11 (18%)
     Other
3 (5%)
5 (8%)

Values are absolute (%) or mean ± SD. APACHE, Acute Physiology and Chronic Health Evaluation; ASA, American Society of Anesthesiologists; P-POSSUM, Portsmouth Physiologic and Operative Severity Score for the enUmeration of Mortality and morbidity.

Pearse et al. Critical Care 2005 9:R687   doi:10.1186/cc3887