Table 3

Tissue perfusion parameters in baboons infused with live Escherichia coli and treated with placebo or anti-L-selectin antibody

Time (hours)

-0.5
 0
 1
 2
 4
 6
 10
 24
 32
 48
 72
aBE (mEQ/l)










     Placebo
 2.7 ± 0.5
 4.0 ± 0.6
 2.4 ± 0.3
 0.8 ± 0.4
 -0.4 ± 0.5
 -0.4 ± 0.5
 -3.4 ± 0.9
 -6.6 ± 0.9
 -2.6 ± 1.3
 3.1 ± 2.6
 7.9 ± 0.6
     L-SEL-Ab
 4.0 ± 0.9
 4.3 ± 0.9
 3.1 ± 0.9
 0.5 ± 1.0
 -0.7 ± 1.2
 -0.8 ± 1.0
 -5.3 ± 1.7
 -10.1 ± 2.6
 -4.8 ± 2.8
 2.2 ± 2.5
 7.3 ± 2.1
Lactate (mmol/l)










     Placebo
 3.4 ± 0.8
 3.3 ± 0.8
 2.4 ± 0.4
 3.5 ± 0.4
 5.2 ± 0.4
 4.9 ± 0.4
 7.3 ± 0.7
 12.1 ± 1.0
 7.8 ± 0.8
 6.7 ± 0.8
 5.2 ± 0.6
     L-SEL-Ab
 3.9 ± 0.9
 3.9 ± 0.9
 1.9 ± 0.2
 4.3 ± 0.7
 6.1 ± 0.9
 6.1 ± 0.7
 9.2 ± 1.4
 14.5 ± 1.9
 9.8 ± 1.0
 6.7 ± 0.8
 6.7 ± 1.1

aBE, arterial base excess; L-SEL-Ab, anti-L-selectin antibody.

Redl et al. Critical Care 2005 9:R735   doi:10.1186/cc3825