|
Characteristics of the study group |
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| All patients (n = 3,147) |
Stratifying according to albumin administration |
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|
|
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| Albumin (n = 354) |
No albumin (n = 2,793) |
p value |
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|
|
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| Age, mean ± SDa |
61 ± 17 |
62 ± 15 |
60 ± 18 |
0.15 |
| Male (%)b |
1,920 (61.7%) |
219 (62.4) |
1,701 (61.6) |
0.776 |
| Chronic diseases (%) |
||||
| COPD |
340 (10.8) |
38 (10.7) |
302 (10.8) |
0.964 |
| Cancer |
415 (13.2) |
66 (18.7) |
349 (12.5) |
<0.001 |
| Heart failure |
307 (9.8) |
42 (11.9) |
265 (9.5) |
0.156 |
| Diabetes |
226 (7.2) |
29 (8.2) |
197 (7.1) |
0.434 |
| Liver cirrhosis |
121 (3.8) |
32 (9.0) |
89 (3.2) |
<0.001 |
| Hematologic cancer |
69 (2.2) |
13 (3.7) |
56 (2.0) |
0.053 |
| HIV/AIDS |
26 (0.9) |
6 (1.7) |
20 (0.7) |
0.18 |
| Surgical admission (%) |
1,388 (44.1) |
218 (61.6) |
1,170 (41.9) |
<0.001 |
| SAPS II score, mean ± SD |
36.5 ± 17.1 |
41.5 ± 17.3 |
35.9 ± 17.0 |
<0.001 |
| Admission SOFA score, mean ± SD |
5.1 ± 3.8 |
6.9 ± 3.9 |
4.9 ± 3.8 |
<0.001 |
| Infection (%) |
1,177 (37.4) |
225 (63.6) |
952 (34.1) |
<0.001 |
| On admission |
777 (24.7) |
140 (39.5) |
637 (22.8) |
<0.001 |
| Severe sepsis (%) |
930 (29.6) |
202 (57.1) |
728 (26.1) |
<0.001 |
| On admission |
552 (17.5) |
112 (31.6) |
440 (15.8) |
<0.001 |
| Septic shock (%) |
462 (16.5) |
144 (40.7) |
318 (11.4) |
<0.001 |
| On admission |
243 (7.7) |
62 (17.5) |
181 (6.5) |
<0.001 |
| ICU stay, median (IQ) |
3.0 (1.7–6.9) |
8.0 (3.1–17.8) |
2.9 (1.6–6) |
<0.001 |
| Hospital stay, median (IQ)c |
15 (7–32) |
27 (12–49) |
14 (7–29) |
<0.001 |
| ICU mortality (%)d |
583 (18.5) |
125 (35.3) |
458 (16.4) |
<0.001 |
| Hospital mortality (%)c |
747 (23.7) |
147 (41.5) |
600 (21.3) |
<0.001 |
|
aNine missing. bThirty-five missing. cThirty-nine missing. dOne missing. ICU, intensive care unit; IQ, interquartile range; SAPS, simplified acute physiology score; SD, standard deviation; SOFA, sequential organ failure assessment. | ||||
Vincent et al. Critical Care 2005 9:R745 doi:10.1186/cc3895 |
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