|
Cox proportional hazard model with time to death, right censored at 30 days, as dependent factor |
||||
| All patients (n = 3,147) |
Propensity matched patients (n = 678) |
|||
|
|
||||
| Relative hazard (95% CI) |
p value |
Relative hazard (95% CI) |
p value |
|
|
|
||||
| SAPS II scorea |
1.04 (1.04–1.05) |
<0.001 |
1.02 (1.01–1.03) |
<0.003 |
| SOFA scoreb |
1.06 (1.03–1.08) |
<0.001 |
1.05 (1.01–1.10) |
0.032 |
| Medical admission |
1.78 (1.25–2.21) |
<0.001 |
2.33 (1.63–3.31) |
<0.001 |
| Age |
1.01 (1.01–1.02) |
<0.001 |
1.02 (1.01–1.03) |
0.003 |
| Cirrhosis |
2.23 (1.68–2.95) |
<0.001 |
1.91 (1.23–2.98) |
0.004 |
| Mean fluid balance |
1.30 (1.24–1.37) |
0.001 |
1.30 (1.19–1.42) |
<0.001 |
| Hemofiltration |
1.25 (1.04–1.50) |
0.019 |
- |
- |
| Albumin administrationb |
1.57 (1.11–2.22) |
0.012 |
1.57 (1.19–2.07) |
0.001 |
| Propensity score |
1.23 (1.12–1.67) |
0.003 |
1.01 (1.01–1.02) |
0.020 |
|
aOn admission. bOn the day of onset of albumin administration in the albumin group and on the day of admission for other patients. CI, confidence interval; SAPS, simplified acute physiology score; SOFA, sequential organ failure assessment. | ||||
Vincent et al. Critical Care 2005 9:R745 doi:10.1186/cc3895 |
||||