Table 3 |
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|
Blood gas analysis and haemodynamic parameters at the end of the 6-hour observational period |
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|
Parameter |
Group 1 (n = 40) |
Group 2 (n = 20) |
P value |
|
|
|||
|
PaO2/FiO2 (mmHg) |
139 ± 68 |
100 ± 68 |
0.046* |
|
PaCO2 (mmHg) |
49 ± 11 |
53 ± 12 |
0.18 |
|
BE (mmol/l) |
-11 ± 4 |
-13 ± 5 |
0.10 |
|
pH |
7.17 ± 0.11 |
7.11 ± 0.13 |
0.06 |
|
Lactate (mmol/l) |
4.3 ± 1.8 |
5.8 ± 3.2 |
0.020* |
|
HR (beats/minute) |
118 ± 20 |
113 ± 20 |
0.48 |
|
CI (l/minute per m2) |
3.2 ± 1.2 |
2.9 ± 1 |
0.39 |
|
LVEF (%) |
50 ± 16 |
48 ± 19 |
0.73 |
|
Vasopressor support (choice; n [%]) |
|||
|
Noradrenaline |
19 (48%) |
9 (45%) |
0.97 |
|
Noradrenaline + dobutamine |
7 (18%) |
4 (20%) |
|
|
Adrenaline |
14 (35%) |
7 (35%) |
|
|
Vasopressor support (dosage; μg/kg per minute) |
1.1 ± 0.8 |
2.3 ± 1.4 |
0.002* |
|
|
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|
Shown is a comparison of blood gas analysis and haemodynamic parameters at the end of the 6-hour observational period between group 1 (responders) and group 2 (nonresponders). Vasopressor dosage is the cumulative dosage of major catecholamines (noradrenaline [norepinephrine] or adrenaline [epinephrine]), with dobutamine being given at 5 μg/kg per minute. *Statistically significant finding. BE, base excess; CI, cardiac index; FiO2, fractional inspired oxygen; HR, heart rate; LVEF, left ventricular ejection fraction; PaCO2, arterial carbon dioxide tension; PaO2, arterial oxygen tension. |
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|
Page et al. Critical Care 2005 9:R755 doi:10.1186/cc3886 |
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