Research
Spontaneous breathing with airway pressure release ventilation favors ventilation in dependent lung regions and counters cyclic alveolar collapse in oleic-acid-induced lung injury: a randomized controlled computed tomography trial
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* Corresponding author: Hermann Wrigge Hermann.Wrigge@ukb.uni-bonn.de
1 Assistant Professor, Department of Anaesthesiology and Intensive Care Medicine, University of Bonn, Sigmund-Freud-Strasse 25, D-53105 Bonn, Germany and Research Fellow, Department of Clinical Physiology, University of Uppsala, University Hospital, SE-751 85 Uppsala, Sweden
2 Physicist and Research Associate, Department of Anaesthesiology and Intensive Care Medicine, University of Bonn, Sigmund-Freud-Strasse 25, D-53105 Bonn, Germany
3 Assistant Professor, Department of Anaesthesiology and Intensive Care Medicine, University of Göttingen, Robert Koch Strasse 40, D-37075 Göttingen, Germany
4 Resident, Department of Anaesthesiology and Intensive Care Medicine, University of Bonn, Sigmund-Freud-Strasse 25, D-53105 Bonn, Germany
5 Professor of Radiology, Department of Radiology, University of Uppsala, University Hospital, SE-751 85 Uppsala, Sweden
6 Professor of Anaesthesiology and Intensive Care Medicine, Department of Anaesthesiology and Intensive Care Medicine, University of Bonn, Sigmund-Freud-Strasse 25, D-53105 Bonn, Germany
7 Professor of Clinical Physiology, Department of Clinical Physiology, University of Uppsala, University Hospital, SE-751 85 Uppsala, Sweden
Critical Care 2005, 9:R780-R789 doi:10.1186/cc3908
See related commentary http://ccforum.com/content/10/1/102
Published: 16 November 2005Additional files
Additional File 1:
Condensed tables from an online supplement presenting cardiorespiratory effects of the same pigs during APRV with and without spontaneous breathing recorded during a different CT study. Data kindly reproduced with permission of Lippincott, Williams and Wilkins, Baltimore, MD, USA. Originally published as: Wrigge H, Zinserling J, Neumann P, Defosse J, Magnusson A, Putensen C, et al.: Spontaneous breathing improves lung aeration in oleic acid-induced lung injury. Anesthesiology 2003, 99:376-384.
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