Table 5 |
|||||
|
Multiple logistic regression model of patient factors in relation to ultimate hospital mortality |
|||||
|
Deaths |
n |
(%) |
Unadjusted OR (95% CI) |
Adjusted OR (95% CI) |
|
|
|
|||||
|
Age |
1.59 (1.46 – 1.73) |
1.57 (1.44 – 1.73) |
|||
|
<55 |
103 |
469 |
(22.0) |
per 10 year increase |
per 10 year increase |
|
55 – 60 |
108 |
395 |
(27.3) |
||
|
60 – 64 |
187 |
556 |
(33.6) |
||
|
65 – 69 |
281 |
745 |
(37.7) |
||
|
70 – 74 |
325 |
747 |
(43.5) |
||
|
75 – 79 |
293 |
537 |
(54.6) |
||
|
80+ |
96 |
162 |
(59.3) |
||
|
Sex |
|||||
|
Female |
630 |
1742 |
(36.2) |
Ref. |
Ref |
|
Male |
763 |
1869 |
(40.8) |
1.19 (1.03 – 1.39) |
1.04 (0.88 – 1.22) |
|
Severe respiratory disease |
|||||
|
No |
827 |
2204 |
(37.5) |
Ref. |
Ref. |
|
Yes |
487 |
1200 |
(40.6) |
1.15 (0.98 – 1.34) |
1.23 (1.03 – 1.46) |
|
Home ventilation |
|||||
|
No |
1288 |
3337 |
(38.6) |
Ref. |
Ref. |
|
Yes |
26 |
67 |
(38.8) |
1.05 (0.62 – 1.78) |
1.16 (0.65 – 2.07) |
|
Steroid treatment in previous 6 months |
|||||
|
No |
1204 |
3110 |
(38.7) |
Ref. |
Ref. |
|
Yes |
110 |
294 |
(37.4) |
0.96 (0.74 – 1.24) |
1.00 (0.75 – 1.33) |
|
Comorbidity: liver disease |
|||||
|
No |
1309 |
3398 |
(38.5) |
Ref. |
Ref. |
|
Yes |
5 |
6 |
(83.3) |
8.22 (0.96 – 70.47) |
3.70 (0.39 – 35.37) |
|
Comorbidity: cardiovascular disease |
|||||
|
No |
1282 |
3326 |
(38.5) |
Ref. |
Ref. |
|
Yes |
32 |
78 |
(41.0) |
1.03 (0.63 – 1.68) |
0.88 (0.51 – 1.50) |
|
Comorbidity: chronic renal failure |
|||||
|
No |
1306 |
3393 |
(38.5) |
Ref. |
Ref. |
|
Yes |
8 |
11 |
(72.7) |
3.29 (0.82 – 13.17) |
2.21 (0.50 – 9.77) |
|
Comorbidity: immunosuppression |
|||||
|
No |
1299 |
3377 |
(38.5) |
Ref. |
Ref. |
|
Yes |
15 |
27 |
(55.6) |
1.92 (0.89 – 4.17) |
1.75 (0.71 – 4.28) |
|
Comorbidity: metastatic cancer |
|||||
|
No |
1310 |
3398 |
(38.6) |
Ref. |
Ref. |
|
Yes |
4 |
6 |
(66.7) |
3.28 (0.60 – 17.96) |
2.50 (0.43 – 14.66) |
|
Length of stay before unit admission (days) |
1.02 (1.01 – 1.03) |
1.02 (1.01 – 1.03) |
|||
|
0 |
567 |
1618 |
(35.0) |
per 1 day increase |
per 1 day increase |
|
1 |
256 |
753 |
(34.0) |
||
|
2 |
111 |
282 |
(39.4) |
||
|
3+ |
449 |
927 |
(48.4) |
||
|
CPR within 24 hours before admission |
|||||
|
No |
1207 |
3291 |
(36.7) |
Ref. |
Ref. |
|
Yes |
176 |
301 |
(58.5) |
2.38 (1.83 – 3.08) |
1.83 (1.37 – 2.45) |
|
Intubation statusa |
|||||
|
Not intubated |
206 |
684 |
(30.1) |
Ref. |
Ref. |
|
Definitely/probably intubated |
1187 |
2927 |
(40.6) |
1.71 (1.38 – 2.13) |
1.36 (1.07 – 1.73) |
|
Lowest pHa |
1.31 (1.23 – 1.40) |
1.23 (1.13 – 1.35) |
|||
|
<7.18 |
391 |
758 |
(51.6) |
per 0.1 decrease |
per 0.1 decrease |
|
7.18–7.25 |
294 |
797 |
(36.9) |
||
|
7.26–7.32 |
259 |
815 |
(31.8) |
||
|
= 7.33 |
297 |
877 |
(33.9) |
||
|
|
|||||
|
|
|||||
|
PaCO2 from ABG with lowest pH (kPa)a |
1.09 (0.91 – 1.29) |
1.01 (0.79 – 1.29) |
|||
|
<6.9 |
334 |
784 |
(42.6) |
per 10 kPa increase |
per 10 kPa increase |
|
6.9–8.6 |
316 |
836 |
(37.8) |
||
|
8.7–10.6 |
270 |
783 |
(34.5) |
||
|
= 10.7 |
320 |
843 |
(38.0) |
||
|
|
|||||
|
PaO2/FiO2 gradient (kPa)a |
1.17 (1.09 – 1.26) |
1.13 (1.04 – 1.22) |
|||
|
<17.2 |
425 |
871 |
(48.8) |
per 10 kPa decrease |
per 10 kPa decrease |
|
17.2–22.8 |
300 |
860 |
(34.9) |
||
|
22.9–29.5 |
293 |
856 |
(34.2) |
||
|
= 29.6 |
294 |
852 |
(34.5) |
||
|
|
|||||
|
Lowest albumin (g/l)a |
|||||
|
<20 |
178 |
303 |
(58.8) |
2.73 (2.11 – 3.54) |
1.94 (1.46 – 2.58) |
|
20–24 |
208 |
477 |
(43.6) |
1.49 (1.20 – 1.84) |
1.28 (1.01 – 1.61) |
|
= 25 or not recorded |
1007 |
2831 |
(35.6) |
Ref. |
Ref. |
|
|
|||||
|
Organ system failure: respiratory |
|||||
|
No |
335 |
786 |
(42.6) |
Ref. |
Ref. |
|
Yes |
1058 |
2825 |
(37.5) |
1.09 (0.87 – 1.36) |
0.71 (0.55 – 0.91) |
|
|
|||||
|
Organ system failure: cardiovascular |
|||||
|
No |
881 |
2594 |
(34.0) |
Ref. |
Ref. |
|
Yes |
512 |
1017 |
(50.3) |
2.21 (1.87 – 2.62) |
1.48 (1.22 – 1.79) |
|
|
|||||
|
Organ system failure: neurological |
|||||
|
No |
1066 |
2978 |
(35.8) |
Ref. |
Ref. |
|
Yes |
327 |
633 |
(51.7) |
1.85 (1.53 – 2.24) |
1.36 (1.10 – 1.68) |
|
|
|||||
|
Organ system failure: renal |
|||||
|
No |
1190 |
3346 |
(35.6) |
Ref. |
Ref. |
|
Yes |
203 |
265 |
(76.6) |
5.17 (3.70 – 7.23) |
3.83 (2.67 – 5.47) |
|
|
|||||
|
Organ system failure: haematological |
|||||
|
No |
1362 |
3550 |
(38.4) |
Ref. |
Ref. |
|
Yes |
31 |
61 |
(50.8) |
1.65 (0.94 – 2.89) |
1.30 (0.69 – 2.45) |
|
|
|||||
|
Ultimate hospital mortality excludes admissions who were readmissions to the intesnive care unit within the same hospital stay, admissions whose ultimate hospital discharge status was missing, and admissions for whom any of the entered risk factors were missing. aDuring first 24 hours following unit admission. ABG, arterial blood gas; CI, confidence interval; CPR, cardiopulmonary resuscitation; FiO2, fractional inspired oxygen; OR, odds ratio; PaCO2, arterial carbon dioxide tension; PaO2, arterial oxygen tension. |
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|
Wildman et al. Critical Care 2005 9(Suppl 3):S38 doi:10.1186/cc3719 |
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