Critical Care

official impact factor 4.60

This article is part of the supplement: Re-establishing organ function in severe sepsis: targeting the microcirculation

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The microcirculation is the motor of sepsis

Can Ince

Critical Care 2005, 9(Suppl 4):S13-S19 doi:10.1186/cc3753

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BioMed Central: 15 citations

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Effects of changes in arterial pressure on organ perfusion during septic shock

Aurélie Thooft, Raphaël Favory, Diamantino Salgado, Fabio S Taccone, Katia Donadello, Daniel De Backer, Jacques Creteur, Jean-Louis Vincent Critical Care 2011, 15:R222 (21 September 2011)

Research article   Open Access

Improvement of Sidestream Dark Field Imaging with an Image Acquisition Stabilizer

Gianmarco M Balestra, Rick Bezemer, E Christiaan Boerma, Ze-Yie Yong, Krishan D Sjauw, Annemarie E Engstrom, Matty Koopmans, Can Ince BMC Medical Imaging 2010, 10:15 (13 July 2010)

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A Review of metabolic staging in severely injured patients

Maria-Angeles Aller, Jose-Ignacio Arias, Alfredo Alonso-Poza, Jaime Arias Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2010, 18:27 (17 May 2010)

Research   Open Access

Near-infrared spectroscopy technique to evaluate the effects of red blood cell transfusion on tissue oxygenation

Jacques Creteur, Ana Neves, Jean-Louis Vincent Critical Care 2009, 13(Suppl 5):S11 (30 November 2009)

Research   Open Access

Changes in skeletal muscle oxygenation during exercise measured by near-infrared spectroscopy on ascent to altitude

Daniel S Martin, Denny ZH Levett, Michael Mythen, Mike PW Grocott, Critical Care 2009, 13(Suppl 5):S7 (30 November 2009)

Research   Open Access

Is thenar tissue hemoglobin oxygen saturation in septic shock related to macrohemodynamic variables and outcome?

Didier Payen, Cecilia Luengo, Laurent Heyer, Matthieu Resche-Rigon, Sébastien Kerever, Charles Damoisel, Marie Losser Critical Care 2009, 13(Suppl 5):S6 (30 November 2009)

Research   Open Access

Assessment of tissue oxygen saturation during a vascular occlusion test using near-infrared spectroscopy: the role of probe spacing and measurement site studied in healthy volunteers

Rick Bezemer, Alexandre Lima, Dean Myers, Eva Klijn, Michal Heger, Peter T Goedhart, Jan Bakker, Can Ince Critical Care 2009, 13(Suppl 5):S4 (30 November 2009)

Research   Open Access

Thoracic epidural anesthesia reverses sepsis-induced hepatic hyperperfusion and reduces leukocyte adhesion in septic rats

Hendrik Freise, Fritz Daudel, Christina Grosserichter, Stefan Lauer, Juergen Hinkelmann, Hugo K Van Aken, Andreas W Sielenkaemper, Martin Westphal, Lars G Fischer Critical Care 2009, 13:R116 (13 July 2009)

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Increasing arterial blood pressure with norepinephrine does not improve microcirculatory blood flow: a prospective study

Arnaldo Dubin, Mario O Pozo, Christian A Casabella, Fernando Pálizas, Gastón Murias, Miriam C Moseinco, Vanina S Kanoore Edul, Fernando Pálizas, Elisa Estenssoro, Can Ince Critical Care 2009, 13:R92 (17 June 2009)

Poster presentation   Free

Tissue perfusion evaluation with near-infrared spectroscopy during treatment with activated protein C

A Donati, L Botticelli, C Anastasi, M Romanelli, L Romagnoli, V Beato, P Pelaia Critical Care 2008, 12(Suppl 2):P67 (13 March 2008)

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Effects of high doses of selenium, as sodium selenite, in septic shock: a placebo-controlled, randomized, double-blind, phase II study

Xavier Forceville, Bruno Laviolle, Djillali Annane, Dominique Vitoux, Gérard Bleichner, Jean-Michel Korach, Emmanuel Cantais, Hugues Georges, Jean-Louis Soubirou, Alain Combes, Eric Bellissant Critical Care 2007, 11:R73 (6 July 2007)

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Activated protein C improves intestinal microcirculation in experimental endotoxaemia in the rat

Christian Lehmann, Konrad Meissner, Andreas Knöck, Stephan Diedrich, Dragan Pavlovic, Matthias Gründling, Taras Usichenko, Michael Wendt, Jürgen Birnbaum Critical Care 2006, 10:R157 (13 November 2006)

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Human malarial disease: a consequence of inflammatory cytokine release

Ian A Clark, Alison C Budd, Lisa M Alleva, William B Cowden Malaria Journal 2006, 5:85 (10 October 2006)

Malariologists tend to think that the pathophysiology of malaria is unique. This thought-provoking review shows that much can be learned from events described with other pathogens and that falciparum malaria is primarily an inflammatory cytokine-driven disease. In particular, the inability of mitochondria, through the effects of inflammatory cytokines, to utilise available oxygen may play a crucial role.

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Bench-to-bedside review: Mechanisms of critical illness – classifying microcirculatory flow abnormalities in distributive shock

Paul WG Elbers, Can Ince Critical Care 2006, 10:221 (19 July 2006)

This article is part of a collection on Translational Research

Research   Open Access

Quantifying bedside-derived imaging of microcirculatory abnormalities in septic patients: a prospective validation study

E Christiaan Boerma, Keshen R Mathura, Peter HJ van der Voort, Peter E Spronk, Can Ince Critical Care 2005, 9:R601-R606 (22 September 2005)