Table 1

Integrative clinical approach for defining a state of shock

Item evaluated
Points

Hemodynamic variables
2
     Heart rate > 100 bpm or

     MAP < 50 mmHg and (CVP < 2 or CVP > 15 mmHg) or

     CI < 2.2 l/min per m2



Peripheral circulation
2
     Mottled skin or

     Tc-Tp difference > 5°C or

     Pfi < 0.3 or

     Impaired peripheral capillary refill

Microvascular variables
1
     Increased tonometric CO2 gap or

     Increased sublingual CO2 gap or

     Impaired sublingual microvascular perfusion (OPS imaging)

Systemic markers of tissue oxygenation
1
     Lactate > 4 mmol/l or

     SvO2 < 60%

Organ dysfunction

     Diuresis < 0.5 ml/kg per houra
1
     Decreased mental statea
1

A state of shock is present if the score exceeds 2 points. CI, cardiac index; CVP, central venous pressure; MAP, mean arterial pressure; OPS, orthogonal polarization spectral imaging; Pfi, peripheral perfusion index; SvO2, mixed venous oxygen saturation; Tc, core temperature; Tp, peripheral toe temperature. aDue to present disease. Reprinted with permission [22].

Trzeciak and Rivers Critical Care 2005 9(Suppl 4):S20   doi:10.1186/cc3744