Critical Care

official impact factor 4.60

This article is part of the supplement: Re-establishing organ function in severe sepsis: targeting the microcirculation

Highly Access Review

Microcirculatory alterations in ischemia–reperfusion injury and sepsis: effects of activated protein C and thrombin inhibition

Johannes N Hoffmann*, Brigitte Vollmar, Matthias W Laschke, Jan M Fertmann, Karl-Walter Jauch and Michael D Menger

Critical Care 2005, 9(Suppl 4):S33-S37 doi:10.1186/cc3758

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