Figure 3.

Effect of activated protein C (APC) on lipopolysaccharide (LPS)-induced (a) arteriolar and (b) venular leukocyte adhesion. The APC group contained animals (n = 8) that received LPS (2 mg/kg) and APC (24 μg/kg per 8 hours intravenously). The control group contained vehicle-treated animals (n = 7) that received LPS (2 mg/kg) only. *P < 0.05, APC animals versus lipopolysaccharide-treated controls (unpaired Student's t-test). ^§P < 0.05, intergroup differences from baseline (paired Student's t-test). Data are the mean ± standard error of mean. Reproduced with permission [30].